Search for dissertations about: "toll-like receptor 4"

Showing result 1 - 5 of 52 swedish dissertations containing the words toll-like receptor 4.

  2. 1. Airway hyperresponsiveness and viral recognizing toll-like receptors

    Author : Magnus Starkhammar; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Common colds caused by viruses are, in healthy individuals, usually self-limited and with relatively mild symptoms. In asthmatic individuals, respiratory viruses can burst the defense immune system and trigger asthma exacerbations, including causing airway hyperresponsiveness (AHR). READ MORE

  4. 2. Renal failure in experimental sepsis : role of endothelin and the toll-like receptor 4

    Author : Johan Fenhammar; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Sepsis is the leading cause of renal failure in critically ill patients, but the pathogenesis of septic kidney dysfunction is poorly defined. The current paradigm states that hypoperfusion and excessive renal vasoconstriction results in renal ischemia. READ MORE

  5. 3. Effects of Inflammatory Mediators on Pulmonary Airways

    Author : Ofir Bachar; Klinisk och experimentell allergiforskning; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; electric ?eld stimulation; bradykinin; airway; tumor necrosis factor a; Respiratory system; nitric oxide; Andningsorganen; Toll-like receptor; prostaglandin E2; neurotrophin; allergy;

    Abstract : Chronic inflammation is together with excessive contraction of the airways key features of asthma. The aims of the thesis were to analyze the effect of inflammatory mediators on airway smooth muscle, using an in vitro model of cultured murine airways. READ MORE

  6. 4. Platelets in inflammation : Role of complement protein C1q, C-reactive proteinand toll-like receptors

    Author : Caroline Skoglund; Torbjörn Bengtsson; Jonas Wetterö; Pentti Tengvall; David Erlinge; Linköpings universitet; []
    Keywords : MEDICINE; MEDICIN;

    Abstract : Platelets are proven essential in haemostasis, however, they are now also increasingly recognized as cells with important immunomodulatory properties, e.g. through interaction with leukocytes and several species of bacteria and by release inflammatory mediators upon activation. READ MORE

  7. 5. Role of TLR4 in Escherichia coli urinary tract infection

    Author : Patrik Samuelsson; immunologi och glykobiologi - MIG Avdelningen för mikrobiologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; mykologi; virologi; mycology; Mikrobiologi; bakteriologi; serologi; transplantation; Microbiology; virology; bacteriology; Immunologi; serology; Immunology; Pathogen; Mucosa; P-fimbriae; Toll like receptor;

    Abstract : In this thesis we have used P fimbriated E. coli as a model to investigate the mechanisms of bacterial recognition and cell activation by the urinary tract (UT) epithelium. We show that Toll like receptor 4 (TLR4) is crucial for the recognition and host response to P fimbriated E. coli. READ MORE