Search for dissertations about: "topical delivery"
Showing result 1 - 5 of 9 swedish dissertations containing the words topical delivery.
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1. Topical formulations, design and drug delivery : "A dive into water"
Abstract : Water is a vital component regulating the properties of topical formulations and their interaction with biological barriers, such as skin and mucosa. Changing the watercontent within the frame of the pharmaceutical triangle will have a huge impact on which type of formulation, such as a cream, ointment, gel, or lotion, is formed, as well as the physical properties of the formulation. READ MORE
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2. Lipid-based liquid crystals as drug delivery vehicles for antimicrobial peptides
Abstract : The development of antimicrobial resistance is a great challenge within health sectors worldwide. Thus, demand for new, efficient treatments is urgent in order to treat various bacterial infections. Antimicrobial peptides (AMPs) are a group of antibiotics that have gained more and more attraction in the past decade. READ MORE
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3. Accelerated wound healing by on-site production and delivery of CXCL12
Abstract : Non-healing wounds is a growing medical problem, often associated with pathological conditions such as diabetes and peripheral ischemia. A non-healing wound entails a large amount of suffering for the patient, and demands extensive health care resources. READ MORE
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4. Foreign molecules in biomembranes : Molecular effects on intact stratum corneum and model lipid systems
Abstract : This thesis mainly explores how the molecular mobility of lipid and protein components in the outermost layer of the skin, the stratum corneum (SC), varies with different conditions and upon adding foreign compounds. These studies require methods that makes it possible to detect and characterize the minor amount of fluid components in the highly ordered solid SC sample with resolved molecular information. READ MORE
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5. Promoting healing of skin and mucosa by immunomodulation using CXCL12 producing lactic acid bacteria : From bench to bedside
Abstract : Immunotherapies direct the immune system to respond in a certain way, such as to fight cancer or to dampen inflammation. In this thesis, a new immunotherapy, ILP100, is developed using a technology that allows for local production of short-lived immunoregulatory proteins that previously have been undruggable. READ MORE