Search for dissertations about: "toremifene"

Found 1 swedish dissertation containing the word toremifene.

2. 1. Analysis of DNA adducts formed by tamoxifen and related antiestrogenic and estrogenic compounds in rats

   Author : Heli Rajaniemi; Karolinska Institutet; Karolinska Institutet; []
   Keywords : DNA adducts; 32P-postlabelling; tamoxifen; toremifene; diethylstilbestrol; clomiphene; triparanol; raloxifene; antiestrogen; estrogen; SERM; genotoxicity; cancer;

   Abstract : The work presented herein has focused on DNA adduct formation by the non-steroidal antiestrogen tamoxifen and its analogues. Tamoxifen, [(Z)-1-{4-[2-(dimethylamino)-ethoxy]phenyl}-1,2-diphenyl-1-butene], is widely used in the treatment of breast cancer and its recognised side effect is endometrial cancer. READ MORE