Search for dissertations about: "toxic equivalency factor"

Found 3 swedish dissertations containing the words toxic equivalency factor.

  2. 1. Properties and analysis of dioxin-like compounds in marine samples from Sweden

    Author : Kjell Lundgren; Umeå universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Environmental chemistry; planar dioxin-like compound; polychlorinated dibenzofuran; polychlorinated biphenyl; polychlorinated naphthalene; alkylated polychlorinated dibenzofuran; high-performance liquid chromatography; PX-21 carbon column; biomagnification factor; biota to sediment accumulation factor; fluxes; relative retention time; mass spectrometry; relative response factor; ultra-violet spectroscopy; Miljökemi; Environmental chemistry; Miljökemi; analytisk kemi; Analytical Chemistry;

    Abstract : Polychlorinated dibenzo-p-dioxins (PCDDs) and dibenzofurans (PCDFs), and dioxin-like polychlorinated biphenyls (PCBs) have been assigned toxic equivalency factors (TEFs). These compounds are today routinely analysed with sophisticated analytical techniques. READ MORE

  4. 2. Computational methods for analyzing dioxin-like compounds and identifying potential aryl hydrocarbon receptor ligands : multivariate studies based on human and rodent in vitro data

    Author : Malin Larsson; Patrik Andersson; Anna Linusson; Mats Tysklind; Scott Boyer; Umeå universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; dioxin-like compounds; multivariate analysis; toxic equivalency factor; quantitative structure-activity relationship; descriptors; virtual screening; in vitro; species variation; aryl hydrocarbon receptor;

    Abstract : Polychlorinated dibenzo-p-dioxins/dibenzofurans (PCDD/Fs) and polychlorinated biphenyls (PCBs) are omnipresent and persistent environmental pollutants. In particular, 29 congeners are of special concern, and these are usually referred to as dioxin-like compounds (DLCs). READ MORE

  5. 3. Mechanistical studies on gap junctions and their role in tumour promotion : structure-activity relationships of polychlorinated biphelyls

    Author : Yvonne Bager; Karolinska Institutet; Karolinska Institutet; []
    Keywords : gap junctional intercellular communication; phosphorylation; tumour promotion; alteredhepatic foci; rat liver; potency; PCBs; TCDD.Doctoral Thesis Yvonne Bager;

    Abstract : Chemically induced carcinogenesis is a multi-stage process that can be divided into at least three major stages, initiation, promotion and progression. The promotion stage involves clonal expansion of genetically altered cells (i.e. initiated cells). READ MORE