Search for dissertations about: "toxicity"

Showing result 16 - 20 of 965 swedish dissertations containing the word toxicity.

  1. 16. Tissue-Selective Activation and Toxicity of Substituted Dichlorobenzenes : Studies on the Mechanism of Cell Death in the Olfactory Mucosa

    Author : Anna Franzén; Eva Brittebo; Ingvar Brandt; Olavi Pelkonen; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Toxicology; tissue-selective toxicity; bioactivation; olfactory mucosa; substituted dichlorobenzenes; Bowman s glands; sustentacular cells; ER stress; Grp78; caspase-12; caspase-3; CYP2A5; protein adduction; nasal toxicity; Toxikologi; Toxicology; Toxikologi;

    Abstract : The nasal passages are constantly exposed to both air- and bloodborne foreign compounds. In particular, the olfactory mucosa is demonstrated to be susceptible to a variety of drugs and chemicals. READ MORE

  2. 17. Small bowel obstruction and toxicity of a new model of adhesion prevention

    Author : Karolin Isaksson; Lund Kirurgi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; small bowel obstruction; predictive parameters; appendectomy; open versus laparoscopic; abdominal adhesions; prevention; polypeptides; toxicity; biodistribution;

    Abstract : Abstract Background: Small bowel obstruction (SBO) is a common surgical diagnosis. If no signs of strangulation are evident, the majority of the patients can be conservatively managed. Approximately one third of the patients need surgical treatment and there is a need for early parameters that can predict operative intervention. READ MORE

  3. 18. Characterization, toxicity and treatment of wood leachate generated outdoors by the wood-based industry

    Author : Henric Svensson; Linnéuniversitetet; []
    Keywords : LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES; Wood leachate; Log yard runoff; Stormwater; Toxicity; Artemia salina; Vibrio fischeri; Constructed wetlands; Forestry and Wood Technology; Skog och träteknik;

    Abstract : Wood is a natural raw material, and would hardly be considered a risk to the environment. However, the handling of wood materials on an industrial scale has been shown to have a negative impact on water bodies that run-off from industrial sites that process wood-based materials. READ MORE

  4. 19. Individually Tailored Toxicity-based Chemotherapy : Studies on Patients with Primary and Metastatic Breast Cancer

    Author : Henrik Lindman; Jonas Bergh; Carl Blomqvist; Peter Nygren; Bo Nordenskjöld; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Oncology; breast cancer; tailored chemotherapy; toxicity-based dosing; high-dose therapy; MR imaging; G-CSF; epirubicin; docetaxel; cyclophosphamide; 5-fluorouracil; Onkologi; Oncology; Onkologi;

    Abstract : Standard dosing of chemotherapy based on body surface area (BSA) results in large individual differences in toxicity due to a large inter-patient variability in pharmacokinetics (PK) and pharmacodynamics (PD). This results in under-dosing in certain patients with a potentially weaker antitumoral effect. READ MORE

  5. 20. Advancing life cycle assessment of textile products to include textile chemicals. Inventory data and toxicity impact assessment

    Author : Sandra Roos; Chalmers tekniska högskola; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Chemicals; Textile; Toxicity; Life cycle assessment; LCA; Inventory; Impact assessment;

    Abstract : Textile products are used by almost everybody throughout the world, fulfilling basic human needs such as keeping us warm and contributing to our social position. Every year the global textile industry delivers close to 100 million metric tonnes of new products to the market. READ MORE