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Showing result 1 - 5 of 8 swedish dissertations matching the above criteria.

  2. 1. Forensic Toxicological Aspects of Tramadol : Focus on Enantioselective Drug Disposition and Pharmacogenetics

    Author : Pernilla Haage; Fredrik Kugelberg; Robert Kronstrand; Espen Molden; Linköpings universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : One of the most difficult parts in forensic toxicology is to interpret obtained drug concentrations. Was it therapeutic, toxic or even lethal to the particular individual that the blood sample was drawn from? Concentrations of opioid drugs are especially difficult to interpret, because of large interindividual differences in innate and acquired tolerance. READ MORE

  4. 2. Central nervous system targets for micturition control

    Author : Rikard Pehrson; Avdelningen för klinisk kemi och farmakologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; central nervous system; Micturition; 5-HT; GABA; tramadol; NAD-299; CGP62349; apomorphine; cerebral infarction; toxikologi; farmaci; farmakognosi; Farmakologi; toxicology; pharmacy; pharmacognosy; Pharmacological sciences;

    Abstract : Normal urine storage and bladder emptying are controlled by the central (CNS) as well as the peripheral nervous system. Dysfunction of these mechanisms can lead to urinary incontinence. Urinary tract dysfunctions have symptomatically been treated mainly with drugs acting peripherally. READ MORE

  5. 3. Day surgery; routines, pain and recovery

    Author : Metha Brattwall; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; day surgery pain routines recovery nausea and vomiting nicotine postoperative pain analgesics tramadol etoricoxib snuff EQ-5d health profile self-assessed questionnaire follow-up;

    Abstract : Day surgery in Sweden is increasing both in numbers and in types of procedures. Also older and sicker patients are often included in day case surgery programs, which puts an extra demand on good practice. Methods: Study I: Questionnaires regarding routines used in 2005 were sent to all day surgery clinics in Sweden. READ MORE

  6. 4. Practical and clinical use of opioids

    Author : Salumeh Bastami; Srinivas Uppugunduri; Johan Ahlner; Peter Höglund; Linköpings universitet; []
    Keywords : ;

    Abstract : Pain is a common symptom of a number of conditions including cancer and one of the most frequent reasons for seeking healthcare. Acute and chronic pain result in considerable discomfort with a detrimental impact on the quality of life. Opioids are the mainstay of pain management for many patients with severe pain. READ MORE

  7. 5. Pain in patients with osteoarthritis treated with total knee arthroplasty

    Author : Henrik Lundblad; Karolinska Institutet; Karolinska Institutet; []
    Keywords : pain;

    Abstract : Background: The pathogenesis and mechanisms of pain in osteoarthritis (OA) are virtually unknown. In the absence of specific and effective pharmacological treatment, joint replacement often remains the only option. Total knee arthroplasty (TKA) has a significant effect in terms of pain relief. READ MORE