Search for dissertations about: "transactivation domain"

Showing result 1 - 5 of 48 swedish dissertations containing the words transactivation domain.

  2. 1. Transcriptional regulation of the Epstein-Barr virus latent membrane protein 1 gene in B cells

    Author : Weiwen Yang; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Epstein-Barr virus; B-cell; transformation; LMP1; LRS; EBNA2; transcription; transactivation; repression; histone deacytylation;

    Abstract : Epstein-Barr Virus (EBV) is a ubiquitous human B-lymphotrobic herpesvirus that latently infects over 90 percent of the world´s population. EBV infection is usually benign in healthy people. READ MORE

  4. 2. THE ANDROGEN RECEPTOR GGN POLYMORPHISM. Genetic and functional analyses

    Author : Kristina Lundin; Avdelningen för klinisk genetik; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medicine human and vertebrates ; Functional domain; Genetic predisposition; Reproductive function; Sex hormone; Transactivation function; Repeat; Polymorphism; Androgen receptor; Transcription factor; Medicin människa och djur ; Endocrinology; secreting systems; diabetology; Endokrinologi; sekretion; diabetologi;

    Abstract : Male sex development and reproductive function is regulated by androgens acting via the androgen receptor (AR). The AR harbours two polymorphic repeats of CAG and GGN triplets, encoding glutamines and glycines, respectively. READ MORE

  5. 3. The life and death of the notch intracellular domain

    Author : Camilla Öberg; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : The Notch signaling pathway is an evolutionarily conserved way of communicating between cells that contact each other. Notch is a single-transmembrane spanning receptor that interacts with single-transmembrane spanning ligands on adjacent cells. In vertebrates the Notch family of receptor consists of four members: Notch1 to Notch4. READ MORE

  6. 4. Gene regulation by the glucocorticoid receptor : post-DNA binding mechanisms of transcriptional activation

    Author : Tova Almlöf; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Gene activation; Glucocorticoid receptor; Nuclear receptor; Transactivation domain; Transcription; Transcription factor; Yeast;

    Abstract : The glucocorticoid receptor (GR) is a ligand-inducible transcription factor that belongs to the nuclear receptor family. The GR has important functions in cellular differentiation, development and metabolism in higher eukaryotes. READ MORE

  7. 5. Chromatin remodeling complexes involved in gene activation by the glucocorticoid receptor

    Author : Annika Wallberg; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : The glucocorticoid receptor (GR) belongs to a large family of ligand-inducible nuclear receptors and consists of a ligand binding domain, a DNA binding domain and transactivation domains. The main transcriptional activation domain, c1, is located in the N-terminus of the receptor. The r1c represents the minimal core activation domain of r1. READ MORE