Search for dissertations about: "transcript analysis"

Showing result 1 - 5 of 150 swedish dissertations containing the words transcript analysis.

  2. 1. Transcript profiling of small tissue samples using microarray technology

    Author : Maria Sievertzon; Joakim Lundeberg; Tom Freeman; KTH; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Biology; Gene expression analysis; transcriptomics; microarray analysis; 3’-tag signature amplification; neural stem cells; Biologi; Biology; Biologi;

    Abstract : Through a number of biological, technological and computational achievements during the 20th century and the devoted work of hundreds of researchers the sequence of the human and other genomes are now available in public databases. The current challenge is to begin to understand the information encoded by the DNA sequence, to elucidate the functions of the proteins and RNA molecules encoded by the genes as well as how they are regulated. READ MORE

  4. 2. Computational Analysis of Tumour Heterogeneity

    Author : Stefanie Friedrich; Erik Sonnhammer; Martin Hemberg; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; tumour heterogeneity; human genome and gene expression analyses; pathway annotation; fusion transcript detection; copy number calling; and high-resolution data; Biochemistry towards Bioinformatics; biokemi med inriktning mot bioinformatik;

    Abstract : Every tumour is unique and characterised by its genetic, epigenetic, phenotypic, and morphological signature. The diversity observed between and within tumours, and over time, is termed tumour heterogeneity. An increased heterogeneity within a tumour correlates with cancer progression, higher resistance rates, and poorer outcome. READ MORE

  5. 3. Vitreoscilla hemoglobin. In vitro mutagenesis and transcript profiling to improve its biotechnological usefulness

    Author : Charlotte Andersson; Tillämpad biokemi; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Biochemical technology; Biokemisk teknik; gene expression analysis; transcript profiling; microarray; DNA chips; microaerobic; hypoxia; oxygen-limited; bacterial hemoglobin; Escherichia coli; Vitreoscilla hemoglobin VHb ;

    Abstract : Vitreoscilla is an obligate aerobic bacterium found in oxygen-poor environments such as stagnant ponds and decaying vegetable matter. Vitreoscilla induces the production of a homodimeric hemoglobin (VHb) when subjected to oxygen-limiting conditions. READ MORE

  6. 4. Cloning and characterization of three Family 9 cellulases from plants and fungi

    Author : Ulla Rudsander; KTH; []
    Keywords : endglucanase; hybrid aspen; cellulose biosynthesis; white rot fungus; homology model; heterologous expression; transcript analysis;

    Abstract : .... READ MORE

  7. 5. Systems Biology in Saccharomyces cerevisiae. Statistical data analysis and mathematical methods

    Author : Roberto Olivares Hernandez; Chalmers tekniska högskola; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Transcriptome; Systems Biology; Proteome; Integrative Analysis; Fluxome;

    Abstract : Over the last decade, Systems Biology has emerged as a new paradigm in the study of cellular systems which are characterized from a global perspective; in contrast to the traditional cellular biology, which was focused on specific components of the cell. To this end, a key milestone for the achievement of a global view of biology is the generation and interpretation of different datasets derived from omics technologies; such as Transcriptome and Proteome. READ MORE