Search for dissertations about: "transcription factor binding sites"

Showing result 1 - 5 of 122 swedish dissertations containing the words transcription factor binding sites.

  2. 1. lac of Time : Transcription Factor Kinetics in Living Cells

    Author : Petter Hammar; Johan Elf; Antoine van Oijen; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; gene regulation; transcription factor; lac operon; facilitated diffusion; single molecule imaging; Molecular Biotechnology; Molekylär bioteknik;

    Abstract : Gene regulation mediated by transcription factors (TFs) is essential for all organisms. The functionality of TFs can largely be described by the fraction of time they occupy their regulatory binding sites on the chromosome. DNA-binding proteins have been shown to find their targets through facilitated diffusion in vitro. READ MORE

  4. 2. Determination of transcription factor binding specificities

    Author : Arttu Jolma; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : The term "genetic code" refers to the way in which the information encoded in nucleic acids is converted into the amino-acid sequence of proteins. There is however also a second genetic code, one that is used by the cells to read the blueprints of the entire organism. READ MORE

  5. 3. Statistical models of TF/DNA interaction

    Author : Aymeric Fouquier d'Herouel; Erik Aurell; Otto Berg; KTH; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; gene expression; regulation; transcription factor; binding motif; matrix representations; gibbs sampling; binding affinity; non-specific binding; Biological physics; Biologisk fysik;

    Abstract : Gene expression is regulated in response to metabolic necessities and environmental changes throughout the life of a cell. A major part of this regulation is governed at the level of transcription, deciding whether messengers to specific genes are produced or not. READ MORE

  6. 4. Regulation of immunoglobulin transcription

    Author : David Liberg; Immunologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; N-substituted benzamides; NFkB; transcription; B cells; immunoglobulin; Immunology; serology; transplantation; Immunologi; serologi;

    Abstract : Each Ig V-region has its own upstream promoter and the promoter of a mature Ig gene is thereby selected during the V(D)J recombination process. Upon comparison, it is evident that only one transcription factor binding site, the octamer, is preserved within all promoters. READ MORE

  7. 5. Functional collaboration between HLH transcription factors in B cell development

    Author : Ramiro Gisler; Stamcellscentrum (SCC); []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; E47; Early B cell Factor EBF ; Clinical genetics; Klinisk genetik; HLH proteins; transcription factors; gene expression; B cell development; transcription regulation;

    Abstract : The cells in B cell development can be divided into several subgroups or fractions, e.g. early-pro-B-, pro-B, large-pre-B-, small-pre-B-, immature and mature B cells, where the stages reflect the maturity degree of the cells. READ MORE