Search for dissertations about: "transcription factor"

Showing result 21 - 25 of 1046 swedish dissertations containing the words transcription factor.

2. 21. Tissue specific functions of Early B-cell factor in cellular differentiation

   Author : Anna Lagergren; Stamcellscentrum (SCC); []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; transcription factor; extracellular fluids; Haematology; tissue specific; cellular differentiation; EBF; Hematologi; extracellulära vätskor;

   Abstract : This work focus on the functions by which the transcription factor Early B-cell Factor (EBF) regulate gene expression in different cell types. To address this question, gene expression analyses aimed to investigate the regulatory role of EBF in neuroblastoma cells, B-lymphocytes, adipocytes and stromal cells were performed. READ MORE

4. 22. Functional Characterization of the Cellular Protein p32 : A Protein Regulating Adenovirus Transcription and Splicing Through Targeting of Phosphorylation

   Author : Christina Öhrmalm; Göran Akusjärvi; Neus Visa; Uppsala universitet; []
   Keywords : Cell and molecular biology; Adenovirus; p32; ASF SF2; E4-ORF4; Splicing; Transcription; CTD; RNA Pol II; Cell- och molekylärbiologi;

   Abstract : Cellular processes involved in the conversion of the genetic information from DNA into a protein are often regulated by reversible phosphorylation reactions. By modulating the phosphorylated status of key proteins their activity can either be enhanced or repressed. READ MORE

5. 23. Crosstalk between Inflammation and Coagulation in Acute Pancreatitis - Experimental and Clinical Studies

   Author : Ellen Andersson; Lund Kirurgi; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; inflammation; acute pancreatitis; active site inactivated factor VII; bleeding; coagulation; factor VII; FVIIai; hemorrhagic complications; hemorrhage; interleukin-6; MIP-2; nuclear factor kappa B; tissue factor;

   Abstract : In various inflammatory conditions a close interplay between inflammation and coagulation is known to exist, where coagulation factor VII (FVII) and tissue factor (TF) are considered to be pivotal players. In this thesis the crosstalk between inflammation and coagulation in acute pancreatitis (AP) has been investigated. READ MORE

6. 24. The Role of Hox Transcription Factors in the Regulation of Hematopoiesis

   Author : Mattias Magnusson; Avdelningen för molekylärmedicin och genterapi; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Hematologi; extracellulära vätskor; extracellular fluids; Haematology; Hox genes; Knockout; Hematopoietic stem cells; Hematopoiesis; Transcription Factor;

   Abstract : Hematopoiesis is a lifelong, dynamic process, originating from a low number of hematopoietic stem cells (HSCs) residing in the adult bone marrow with the ability to self-renew and generate all blood lineages throughout life. Recent findings have demonstrated that the Homeobox (Hox) transcription factors are important regulators of both normal and malignant hematopoiesis, controlling proliferation, differentiation and self-renewal of hematopoietic cells at different levels of the hematopoietic hierarchy. READ MORE

7. 25. Interplay between Transcription and Homologous Recombination in the Presence of DNA Damage

   Author : Ivaylo Stoimenov; Thomas Helleday; Niklas Schultz; Natalia Issaeva; Thierry Nouspikel; Stockholms universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; homologous recombination; transcription; DRB; UVC; 6-thioguanine; mammalian cells; BRCA1; BRCA2; PARP inhibitors; XP-V; Molecular biology; Molekylärbiologi; molekylärgenetik; Molecular Genetics;

   Abstract : The biochemical processes of DNA repair, replication and recombination compete for the same substrate, the DNA molecule. This competition is natural, as each process requires the same template. In order to resolve possible conflicts between these processes, when they take place on a particular stretch of DNA, certain crosstalk is expected. READ MORE