Search for dissertations about: "transcriptional regulation"

Showing result 1 - 5 of 685 swedish dissertations containing the words transcriptional regulation.

  1. 1. The Multifunctional HnRNP A1 Protein in the Regulation of the Cyp2a5 Gene Connecting Transcriptional and Posttranscriptional Processes

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Tina Glisovic; Matti Lang; Francoise Raffalli-Mathieu; Lorenz Poellinger; [2003]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmaceutical biochemistry; Cyp2a5; DNA-protein interaction; gene regulation; hnRNP A1; nucleocytoplasmic shuttling; RNA-protein interaction; RNA stabilization; posttranscriptional; transcriptional; Farmaceutisk biokemi; PHARMACY Pharmaceutical biochemistry; FARMACI Farmaceutisk biokemi;

    Abstract : The mouse xenobiotic-inducible Cyp2a5 gene is both transcriptionally and posttranscriptionally regulated. One of the most potent Cyp2a5 inducers, the hepatotoxin pyrazole, increases the CYP2A5 mRNA half-life. READ MORE

  2. 2. An analytical framework for studying transcriptional regulation

    University dissertation from Gothenburg : Chalmers tekniska högskola

    Author : Christoph Sebastian Börlin; [2020]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; transcription factor; ChIP-exo; S. cerevisiae; transcriptional regulation;

    Abstract : The state and behavior of any living cell is controlled by a complex interplay of different regulatory processes, with the regulation of transcription playing a major role. When a cell adapts to a new environment it often does that by modulating gene transcript levels, mainly through changes in transcription factor binding events. READ MORE

  3. 3. Decoding the Structural Layer of Transcriptional Regulation Computational Analyses of Chromatin and Chromosomal Aberrations

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Robin Andersson; Jan Komorowski; Jan Dumanski; Claes Wadelius; Anders Krogh; [2010]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Chromatin; Nucleosome positioning; Histone modifications; Chromosomal aberrations; Transcriptional regulation; Array-CGH; Next generation sequencing; ChIP-chip; NATURAL SCIENCES Biology Other biology Bioinformatics; NATURVETENSKAP Biologi Övrig biologi Bioinformatik; Bioinformatics; Bioinformatik;

    Abstract : Gene activity is regulated at two separate layers. Through structural and chemical properties of DNA – the primary layer of encoding – local signatures may enable, or disable, the binding of proteins or complexes of them with regulatory potential to the DNA. READ MORE

  4. 4. Small RNAs, Big Consequences Post-transcriptional Regulation and Adaptive Immunity in Bacteria

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Mirthe Hoekzema; Gerhart E. H. Wagner; Magnus Lundgren; Kai Papenfort; [2018]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; small RNA; sRNA; non-coding RNA; Hfq; gene regulation; post-transcriptional regulation; biofilm; OmrA; OmrB; toxin-antitoxin; TisB; IstR-1; Persisters; CRISPR-Cas; CRISPR-Cas adaptation reporter; Escherichia coli; Biologi med inriktning mot mikrobiologi; Biology with specialization in Microbiology;

    Abstract : It is nowadays widely accepted that non-coding RNAs play important roles in post-transcriptional regulation of genes in all kingdoms of life. In bacteria, the largest group of RNA regulators are the small RNAs (sRNAs). READ MORE

  5. 5. The Cyanobacterial Uptake Hydrogenase Regulation, Maturation and Function

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Marie Holmqvist; Peter Lindblad; Karin Stensjö; Kornél Kovács; [2010]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Biohydrogen; CalA; Cyanobacteria; Hydrogenase; Maturation; Nostoc punctiforme ATCC 29133; Nostoc sp. PCC 7120; Transcriptional regulation; NATURAL SCIENCES Biology Cell and molecular biology Molecular biology; NATURVETENSKAP Biologi Cell- och molekylärbiologi Molekylärbiologi; NATURAL SCIENCES Chemistry Biochemistry Molecular biology; NATURVETENSKAP Kemi Biokemi Molekylärbiologi; Chemistry with specialization in Microbial Chemistry; Kemi med inriktning mot mikrobiell kemi;

    Abstract : With accellerating global warming and pollution problems a change of energy regime is necessary. Solar energy offers a clean and unlimited energy source of enormous potential. Due to it’s intermittenet nature solar energy must be stored - ideally in the chemical bond of a carrier molecule. READ MORE