Search for dissertations about: "transcriptional regulation"

Showing result 11 - 15 of 767 swedish dissertations containing the words transcriptional regulation.

  2. 11. Post-Transcriptional Regulation of the Murine Inducible Nitric Oxide Synthase Gene

    Author : Malin Söderberg; Matti A. Lang; Françoise Raffalli-Mathieu; Eeva Moilanen; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmaceutical biochemistry; iNOS; inducible nitric oxide synthase; gene regulation; post-transcriptional; mRNA stability; RNA-protein interactions; dexamethasone; murine; heterogeneous nuclear ribonucleoprotein; hnRNPI; hnRNPL; Farmaceutisk biokemi; Pharmaceutical biochemistry; Farmaceutisk biokemi;

    Abstract : Large amounts of nitric oxide (NO) are produced by the inducible nitric oxide synthase (iNOS) upon inflammatory stimuli. NO is a multifaceted molecule, which may have beneficial effects as an antimicrobial agent in the immune defense, or cytotoxic effects in chronic inflammations, manifested as e.g. arthritis and asthma. READ MORE

  4. 12. Post-transcriptional regulation after stress in Schizosaccharomyces pombe

    Author : Daniel Nilsson; Göteborgs universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Post transcriptional regulation;

    Abstract : Post transcriptional regulation is part of the gene expression control and is important for many cellular processes. It influences how mRNAs are selected for translation, degradation or storage. In this thesis, I describe some of the known mechanisms for transcriptional regulation in S. READ MORE

  5. 13. Post-transcriptional regulation by RNases in Streptococcus pyogenes

    Author : Anne-Laure Lécrivain; Emmanuelle Charpentier; Bernt Eric Uhlin; Tracy Nissan; Ciarán Condon; Umeå universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Post-transcriptional regulation; mRNA decay; RNA sequencing; RNase Y; RNase III; YhaM; PNPase; RNase R; RNase J1; Streptococcus pyogenes.; molekylärbiologi; Molecular Biology;

    Abstract : Ribonucleases (RNases) are proteins that adjust cellular RNA levels by processing RNA transcripts, leading to their stabilization or degradation. RNases are grouped based on their ability to cleave the transcript internally (endoRNases) or degrade the transcript starting from the ends (exoRNases). READ MORE

  6. 14. Regulation of Vitamin D 25-hydroxylases : Effects of Vitamin D Metabolites and Pharmaceutical Compounds on the Bioactivation of Vitamin D

    Author : Maria Ellfolk; Kjell Wikvall; Maria Norlin; Olavi Pelkonen; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; CYP2D25; vitamin D 25-hydroxylase; transcriptional regulation; vitamin D; CYP2R1; CYP2J2; CYP27A1; phenobarbital; efavirenz; fibroblast; LNCaP; Pharmaceutical biochemistry; Farmaceutisk biokemi;

    Abstract : A 700bp portion of the promoter of CYP2D25, the porcine microsomal vitamin D 25-hydroxylase was isolated and sequenced. The computer analysis of the sequence revealed the existence of a putative VDRE at 220 bp upstream of the transcription start site. READ MORE

  7. 15. Maturation and Regulation of Cyanobacterial Hydrogenases

    Author : Åsa Agervald; Peter Lindblad; Karin Stensjö; Ann Magnuson; Poul Erik Jensen; Uppsala universitet; []
    Keywords : Biohydrogen; Cyanobacteria; Nostoc sp. PCC 7120; Nostoc punctiforme PCC 73102; Hydrogenase; Maturation; Transcriptional regulation; CyAbrB; CalA; FeSOD;

    Abstract : Accelerated global warming plus an increasing need for energy is an equation not easily solved, thus new forms of sustainable energy production are urgently requested. In this context hydrogen production based on a cyanobacterial system offers an environmentally friendly alternative for energy capture and conversion. READ MORE