Search for dissertations about: "transcriptome analysis"
Showing result 16 - 20 of 190 swedish dissertations containing the words transcriptome analysis.
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16. Computational methods for analysis of spatial transcriptomics data : An exploration of the spatial gene expression landscape
Abstract : Transcriptomics techniques, whether in the form of bulk, single cell/nuclei, or spatial methods have fueled a substantial expansion of our knowledge about the biological systems within and around us. In addition, the rate of innovation has accelerated over the last decade, resulting in a multitude of technological advances and new methods for generation of transcriptomics data. READ MORE
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17. Physiology of Saccharomyces cerevisiae Producing Recombinant Insulin in Continuous Culture
Abstract : The yeast Saccharomyces cerevisiae has widely been used as a host for the production of heterologous proteins. High-level production of heterologous proteins is likely to impose a metabolic burden on the host cell and can thus affect various aspects of cellular physiology. READ MORE
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18. Functional characterization of the biological significance of the ZBED6/ZC3H11A locus in placental mammals
Abstract : The recent advances in molecular and computational biology have made possible the study of complicated transcriptional regulatory networks that control a wide range of biological processes and phenotypic traits. In this thesis, several approaches were combined including next generation sequencing, gene expression profiling, chromatin and RNA immunoprecipitation, bioinformatics and genome editing methods in order to characterize the biological significance of the ZBED6 and ZC3H11A genes. READ MORE
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19. Twin-arginine translocation in Yersinia : the substrates and their role in virulence
Abstract : Pathogenic Yersinia cause a manifold of diseases in humans ranging from mild gastroenteritis (Y. pseudotuberculosis and Y. enterocolitica) to pneumonic and bubonic plague (Y. READ MORE
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20. Development and Application of Genomic Resources in Non-model Bird Species
Abstract : Understanding the genetic basis of biological processes is a fundamental component of modern ecology and evolutionary biology studies. With the recent advent of next generation sequencing (NGS) technologies, it is now possible to perform large genome and transcriptome projects for ecologically important non-model species. READ MORE