Search for dissertations about: "transdermal in vitro"
Found 4 swedish dissertations containing the words transdermal in vitro.
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1. Assessment of microvascular effects of vasoactive drugs : Methodological in vivo studies in humansbased on iontophoresis
Abstract : Cardiovascular disease is the leading cause of death in western societies and endothelial dysfunction is one of the earliest signs seen in the development of such conditions. Thedevelopment of prognostic tools to aid in the prediction of micro- and macrovascular diseasebased on assessment of vascular reactivity is therefore of paramount importance. READ MORE
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2. Ceramic Materials for Administration of Potent Drugs
Abstract : This thesis aimed to investigate and document the potential of applying ceramics in two specific drug delivery applications: tamper-resistant opioid formulations and transdermal enhancement protrusions.Geopolymers were developed into the matrix for a tamper-resistant formulation, aiming to protect drug substances from non-medical abuse. READ MORE
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3. Skin hydration - How water and osmolytes influence biophysical properties of stratum corneum
Abstract : The outermost layer of skin (i.e., the stratum corneum, SC) is the interface that separates the water-rich inside of the body from the relatively dry external environment. SC forms an effective permeability barrier, which has to be overcome in transdermal drug delivery. READ MORE
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4. Non-invasive monitoring of low molecular weight biomarkers relevant to skin inflammation and cancer
Abstract : Development of skin inflammation and cancer in viable epidermis and dermis involve slow molecular weight (LMW) metabolites. We hypothesize that these LMW compounds can be collected on the surface of the skin and used for non-invasive diagnostics of skin disorders. READ MORE