Search for dissertations about: "transforming growth factor beta"

Showing result 1 - 5 of 52 swedish dissertations containing the words transforming growth factor beta.

  1. 1. Insulin-like Growth Factor System: functional role and regulation in carcinomas

    University dissertation from Department of Clinical Sciences, Lund University

    Author : Ann Rosendahl; Lunds universitet.; Lund University.; [2007]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cancerology; oncology; Cytology; PTEN; Transforming Growth Factor-beta; Insulin-like Growth Factor; Renal Cell Carcinoma; Cytologi; onkologi; cancer; Endocrinology; secreting systems; diabetology; Endokrinologi; sekretion; diabetologi;

    Abstract : The insulin-like growth factor (IGF) system demonstrates numerous actions during neoplastic growth and is therefore an interesting target with potential clinical implications. While numerous studies have established important roles of the IGF system in regulating cellular growth and survival of several tumor forms, very limited reports exist regarding its role in renal cell carcinoma (RCC). READ MORE

  2. 2. Growth factor regulation of the urokinase plasminogen activator (uPA) system in human endometrium, and the significance of uPA receptor activation in endometrial angiogenesis

    University dissertation from Institutionen för Obstetrik och gynekologi, Universitetssjukhuset, 22185 Lund

    Author : Tove Sandberg; Lunds universitet.; Lund University.; [2000]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Obstetrics; endothelial cell migration; angiogenesis; uPA:PAI-1 complex; uPAR; TGF-beta; PAI-1; EGF; uPA; Growth factor; gynaecology; andrology; reproduction; sexuality; Obstetrik; gynekologi; andrologi; reproduktion; sexualitet;

    Abstract : Popular Abstract in Swedish Avhandlingen studerar tillväxtfaktorernas reglering av uPA-systemet i endometriet, och betydelsen av uPA-receptorns (uPAR) aktivering i den endometriella angiogenesen. Tillväxtfaktorer är polypeptider, vilka fungerar som signalmolekyler i cellernas kommunikation. READ MORE

  3. 3. Transcriptional Regulation ofthe Platelet-Derived Growth Factor beta-receptor

    University dissertation from Institutionen för Obstetrik och gynekologi, Universitetssjukhuset, 22185 Lund

    Author : Anders Hackzell; Göteborgs universitet.; Gothenburg University.; [2004]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; PDGF; cell cycle; p73; p53; SV40; NF-Y; Sp1; Myc;

    Abstract : The Platelet Derived-Growth Factor (PDGF) receptors and ligands are expressed in cells of predominantly mesenchymal origin. Binding of the ligands to the receptors stimulates cell proliferation and other cellular responses such as differentiation and cell movement. READ MORE

  4. 4. Molecular studies of pancreatic cancer: Characterization of the transforming growth factor beta signaling pathway

    University dissertation from Department of Clinical Genetics, Lund University

    Author : Tord Jonson; Lunds universitet.; Lund University.; [2001]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; SMAD4; PCR; FISH; cytogenetics; chromosome; pancreatic cancer; TGFB signaling; cytogenetik; Genetik; Genetics;

    Abstract : Popular Abstract in Swedish Pankreascancer (cancer i bukspottkörteln) drabbar ungefär 900 personer om året i Sverige. Tumörformen har tidigare varit vanligare hos män men är numera lika vanlig hos män och kvinnor. READ MORE

  5. 5. Growth factors in spermatogenesis

    University dissertation from Stockholm : Karolinska Institutet, Department of Women's and Children's Health

    Author : Aida Wahlgren; Karolinska Institutet.; Karolinska Institutet.; [2003]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Testis; seminiferous tubules; proliferation; growth factors; sex steroids;

    Abstract : The aim of this study was to increase the knowledge of die effects of locally produced growth factors and hormones on germ cell proliferation in rat testis in vitro. Since impaired sperm production and function accounts for half the cases of infertility, it is important to understand the physiological actions in germ cell development. READ MORE