Search for dissertations about: "transforming growth factor-B TGFB"

Found 4 swedish dissertations containing the words transforming growth factor-B TGFB.

  2. 1. Chronic pancreatitis fibrogenesis : the role of TGFB pathway inhibitor Smad7 in the fibrosis development

    Author : Xuan Li; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Chronic pancreatitis is characterized by progressive inflammation, acinar atrophy and fibrosis. Transforming growth factor-B signaling (TGFB) is the most potent fibrogenic cytokine known, and its increased expression is a common denominator for fibrosis in chronic pancreatitis. READ MORE

  4. 2. Glial cell line-derived neurotrophic factor : expression patterns, neuronal transport, regulation, effects, and receptor dependence

    Author : Andreas C Tomac; Karolinska Institutet; Karolinska Institutet; []
    Keywords : glial cell line-derived neurotrophic factor GDNF ; neurturin NTN ; persephin PSP ; c Ret proto oncogene Ret ; GPI-linked receptors for the GDNF ligand family GFRas ; transforming growth factor-B TGFB ; Parkinson s disease PD ; dopaminergic DA neurons;

    Abstract : Background: The mammalian nervous system depends upon trophic proteins for survival, growth and adult maintenance. These trophic factors have also been considered as potential therapeutic agents for treating human neurodegenerative disorders. READ MORE

  5. 3. Genetic dissection of tubulogenesis in the Drosophila trachea

    Author : Johanna Hemphälä; Christos Samakovlis; Reinhard Schuh; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Drosophila; trachea; transposon mutagenesis screen; fusion; Dpp; Delta; tubular dimensions; Grainyhead; Krotzkopf verkehrt; intralumenal matrix; Developmental biology; Utvecklingsbiologi;

    Abstract : The formation of branched tubular organs, such as the mammalian lung kidney and vascular system, is an essential process in animal development. The Drosophila tracheal (respiratory) system provides a genetic model system to study the highly ordered process of branch outgrowth and fusion required to form continuous tubular networks. READ MORE

  6. 4. The role of smooth muscle cells in calcification of atherosclerotic plaques

    Author : Till Seime; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Calcification (CALC) is a predominant feature of late-stage cardiovascular disease (CVD) but responsible mechanisms and its contribution to the risk of clinical events remain unclear. Formation of highly mineralized extracellular matrix (ECM) leads to progressive aortic valve stenosis (AVS) and has been identified as a surrogate marker for atherosclerotic disease burden. READ MORE