Search for dissertations about: "translation initiation"

Showing result 6 - 10 of 91 swedish dissertations containing the words translation initiation.

  2. 6. Computational Studies of Protein Synthesis on the Ribosome and Ligand Binding to Riboswitches

    Author : Christoffer Lind; Johan Åqvist; Alexander MacKerell Jr; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Binding free energy; Ribosome; Codon reading; Translation initiation; Translation termination; Mitochondrial translation; Release factor; Purine riboswitch; Molecular Dynamics; Free Energy Perturbation; Biology with specialization in Molecular Biotechnology; Biologi med inriktning mot molekylär bioteknik;

    Abstract : The ribosome is a macromolecular machine that produces proteins in all kingdoms of life. The proteins, in turn, control the biochemical processes within the cell. It is thus of extreme importance that the machine that makes the proteins works with high precision. READ MORE

  4. 7. Ribosome standby sites and other structural aspects of translation initiation regions in Escherichia coli

    Author : Maaike M. Sterk; Gerhart E. H. Wagner; Fredrik Söderbom; Isabella Moll; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Ribosome standby sites; translation initiation; mRNA structure; bacteria;

    Abstract : Translation initiation, which is rate-limiting in protein synthesis, is often the step at which regulation occurs. Here, we investigated several mechanisms of translation initiation in Escherichia coli, including their control. READ MORE

  5. 8. Characterization of land plant-specific proteins required for mitochondrial translation initiation

    Author : Huy Cuong Tran; Molekylär cellbiologi; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Mitochondrial unfolded protein response; Arabidopsis mitochondrial isolation; mitoribosome; mitochondrial translation initiation; mitoribosome small subunit; mTRAN; mTRAN-mRNA interaction;

    Abstract : Plant mitochondria produce the majority of adenosine triphosphate (ATP) – the cellular energy currency for metabolic reactions needed for plant growth, development, and maintenance. Despite a relatively thorough understanding of basic mitochondrial functions, many mitochondrial proteins and processes remain poorly understood. READ MORE

  6. 9. Initiation of Protein Biosynthesis in Skeletal Muscles at Feeding

    Author : Britt-Marie Iresjö; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Protein synthesis; Translation initiation; amino acids; Snat 2; MHC2A; IGF-I;

    Abstract : Background and aim. Artificial nutrition by intravenous feeding has for decades indicated less than optimal support of whole-body protein metabolism and balance during some treatment conditions. READ MORE

  7. 10. Studies on translation initiation and gene expression in Escherichia coli

    Author : Ernesto I. Gonzalez de Valdivia; Leif Isaksson; Stephen Douthwaite; Stockholms universitet; []
    Keywords : Downstream region; NGG codons; abortive translation; drop-off; Shine-Dalgarno sequence; gene expression and Escherichia coli; NATURAL SCIENCES; NATURVETENSKAP;

    Abstract : In prokaryotes, several mRNA sequences surrounding the initiation codon have been found to influence the translation process; these include the downstream region and its codon context, the Shine-Dalgarno sequence and the S1 ribosomal protein-binding site. In this thesis, the purpose has been to study the role of the downstream region and Shine-Dalgarno-like sequences on early translation elongation and gene expression in Escherichia coli. READ MORE