Advanced search

Found 2 swedish dissertations matching the above criteria.

  1. 1. Cis-regulatory variation and divergence in Capsella

    Author : Kim A. Steige; Tanja Slotte; Jeff J. Doyle; Uppsala universitet; []
    Keywords : Capsella; Shepherd s Purse; cis-regulatory changes; allele-specific expression; mating system shift; floral evolution; polyploidy; positive selection; purifying selection; transposable elements; small RNA; methylation; transposable element silencing; distribution of fitness effects;

    Abstract : Cis-regulatory changes in e.g. promoters or enhancers that affect the expression of a linked focal gene have long been thought to be important for adaptation. In this thesis, I investigate the selective importance and genomic correlates of cis-regulatory variation and divergence in the genus Capsella, using massively parallel sequencing data. READ MORE

  2. 2. Population genomic analyses of regulatory variation and selection in Brassicaceae species

    Author : Robert Horvath; Tanja Slotte; Peter Hambäck; Douglas G. Scofield; Matthew Webster; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Capsella grandiflora; Arabidopsis thaliana; Arabidopsis lyrata; natural selection; gene expression variation; DNA and gene body methylation; transposable elements; DNA accessibility; gene expression noise; epigenetic silencing; linked selection; ekologi och evolution; Ecology and Evolution;

    Abstract : The impact of selection on regulatory variation and the contribution of regulatory changes to phenotypic variation has long been debated in evolutionary genetics. Because cis-regulatory elements such as promoters and enhancers can be difficult to identify, it has been more challenging to quantify the impact of selection on variation in cis-regulatory regions than in protein-coding regions. READ MORE