Search for dissertations about: "transposable elements"

Showing result 1 - 5 of 17 swedish dissertations containing the words transposable elements.

  1. 1. Transposable Elements in Neural Progenitor Cells

    University dissertation from Molecular Neurogenetics, Faculty of Medicine, Lund University

    Author : Liana Fasching; Lund University.; Lunds universitet.; Lund University.; Lunds universitet.; [2015]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Transposable Elements; TRIM28; Epigenetic Regulation; Gene Expression; Neural Progenitor Cells;

    Abstract : More than 90% of DNA does not code for proteins and for a long time these sequences were referred to as “junk DNA” due to their unknown purpose. With the advent of new technologies it is now known, that the non-coding part of the genome is of great importance for regulating gene expression and is therefore indispensable. READ MORE

  2. 2. The Epigenetic Impact of Transposable Elements in Human Brain Development

    University dissertation from Lund University: Faculty of Medicine

    Author : Per Ludvik Brattås; Lund University.; Lunds universitet.; Lund University.; Lunds universitet.; Lund University.; Lunds universitet.; [2019]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; transposable elements; epigenetics; neural stem cells; human brain development; gene regulation; human brain evolution;

    Abstract : .... READ MORE

  3. 3. Cis-regulatory variation and divergence in Capsella

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Kim A. Steige; Uppsala universitet.; [2016]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Capsella; Shepherd s Purse; cis-regulatory changes; allele-specific expression; mating system shift; floral evolution; polyploidy; positive selection; purifying selection; transposable elements; small RNA; methylation; transposable element silencing; distribution of fitness effects;

    Abstract : Cis-regulatory changes in e.g. promoters or enhancers that affect the expression of a linked focal gene have long been thought to be important for adaptation. In this thesis, I investigate the selective importance and genomic correlates of cis-regulatory variation and divergence in the genus Capsella, using massively parallel sequencing data. READ MORE

  4. 4. Regulation and mechanism of mating-type switching in Kluyveromyces lactis

    University dissertation from Stockholm : Department of Molecular Biosciences, The Wenner-Gren Institute, Stockholm University

    Author : Naghmeh Rajaei; Stockholms universitet.; [2015]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; yeast; mating-type switching; DSB; gene conversion; transposable elements; RAS cAMP pathway; nutrient limitation; molekylär biovetenskap; Molecular Bioscience;

    Abstract : Transposable elements (TEs) have had immense impact on the structure, function and evolution of eukaryotic genomes. The work in this thesis identified Kat1, a novel domesticated DNA transposase of the hAT family in the yeast Kluyveromyces lactis. Kat1 triggers a genome rearrangement that results in a switch of mating type from MATa to MATα. READ MORE

  5. 5. The Regulatory Role of microRNAs in the Mouse and Human Brain

    University dissertation from Lund University: Faculty of Medicine

    Author : Rebecca Petri; Lund University.; Lunds universitet.; [2017]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; microRNA; Argonaute; AGO-RIP; let-7; miR-125; adult neurogenesis; olfactory bulb; autophagy; transposable elements; LINE-2; Huntington’s disease;

    Abstract : microRNAs (miRNAs) are 20-24 nucleotides small, single-stranded, non-coding RNAs. They associate with Argonaute (AGO) proteins and exert their function by inhibition or degradation of messenger RNAs. READ MORE