Search for dissertations about: "treatment of cancers"

Showing result 21 - 25 of 401 swedish dissertations containing the words treatment of cancers.

  2. 21. Aspects of mechanical dysphagia. Assessment, treatment and consequences

    Author : Jan Persson; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Dysphagia; Watson; Ogilvie; Goldschmid; QoL; Sarcopenia; Laparoscopic myotomy; Achalasia; Oesophageal cancer;

    Abstract : Aspects of mechanical dysphagia Assessment, treatment and consequences Jan Persson, M.D. Department of surgery, Institute of Clinical sciences, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden ABSTRACT Background: Dysphagia is a symptom that negatively impacts patients’ quality of life. READ MORE

  4. 22. Searching for Synergy : Radiosensitization of 177Lu-DOTATATE

    Author : Sara Lundsten; Marika Nestor; Hanna Björkelund; Katarina Edwards; Julie Nonnekens; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cancer; targeted radionuclide therapy; radiosensitization; p53; MDM2 MDM4 inhibition; HSP90; drug synergy; drug delivery; lipid nanoparticles; lipodisks; Biomedical Radiation Science; Biomedicinsk strålningsvetenskap;

    Abstract : Cancers presents a major health challenge, and there is a pressing need to develop new therapeutic strategies. Surgery, chemotherapy and radiation are the most commonly used treatments for cancer today. Radiation can be given as targeted radionuclide therapy (TRT), i.e. READ MORE

  5. 23. Improvement of the diagnosis and management of cystic tumors of the pancreas

    Author : Zeeshan Ateeb; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Pancreatic cancer is on its course on becoming the second cause of cancer related mortality. Although improvements have been made in the treatment arsenal, still only a minority of patients are able to receive treatment with curative intention. READ MORE

  6. 24. Characterizing the spectrum of somatic alterations in canine and human cancers

    Author : Sharadha Sakthikumar; Kerstin Lindblad-Toh; Richard Rosenquist Brandell; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; dog; osteosarcoma; hemangiosarcoma; glioblastoma; non-coding; whole-exome; whole-genome; sequencing; bioinformatics; comparative genetics.;

    Abstract : Cancers arise as a result of deleterious somatic alterations accumulating in the genome during the process of cell division. These alterations arise either via exposure to mutagens or due to errors occurring during DNA replication. READ MORE

  7. 25. Homotrimeric dUTPases : Principles of Catalysis and Inhibitor Design

    Author : Lorena Gonzalez Palmén; Jan Kvassman; Dolores Gonzalez-Pacanowska; Högskolan i Kalmar; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; dUTPases; kinetics; ground state destabilization; inhibitors; Biochemistry; Biokemi; Natural Science; Naturvetenskap;

    Abstract : The ubiquitous enzyme dUTPase hydrolyzes dUTP into dUMP and pyrophosphate, preventing DNA fragmentation and cell death due to accumulation of dUTP. Inhibitors of dUTPase could serve as drugs in the treatment of cancers and infectious diseases. This thesis presents five studies. READ MORE