Search for dissertations about: "treatment outcome in advanced cancer patient"

Showing result 1 - 5 of 33 swedish dissertations containing the words treatment outcome in advanced cancer patient.

  1. 1. Comparative treatment planning in external radiotherapy of malignant tumours : Potential gains using protons

    Author : Ulf Isacsson; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Oncology; Breast cancer; comparative treatment; Ewing sarcoma; oesophageal cancer; protontherapy; radiotherapy; rectal cancer; treatment planning algorithms; Onkologi; Oncology; Onkologi; Oncology; onkologi;

    Abstract : It is well known that protons have physical characteristics superior to conventional radiation qualities in external beam radiotherapy. The primary aim of this work is to determine if the physical advantages also may lead to clinical advantages. READ MORE

  2. 2. Advanced Ovarian Cancer. A multimodal diagnostic approach to predict outcome

    Author : Mihaela Asp; Lund Obstetrik och gynekologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Advanced ovarian cancer; multidisciplinary; tru-cut biopsy; frozen section; peritoneal cancer index; CT; primary debulking surgery; cytoreductive surgery; survival;

    Abstract : Primary debulking surgery (PDS) followed by platinum-based postoperative chemotherapy isthe standard of care for advanced ovarian cancer (AOC). Absence of macroscopic residualdisease after debulking surgery is the strongest prognostic factor achieved by surgery. READ MORE

  3. 3. Head and Neck Cancer: Studies on microvessel density, radiation response and FDG PET

    Author : Eva Brun; Bröstcancer-genetik; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; positron emission tomography PET ; 2-18 fluoro deoxy glucose FDG ; radiotherapy; microvessel density; Head and neck cancer; therapy response; Cytology; oncology; cancerology; Cytologi; onkologi; cancer;

    Abstract : Treatment options of head and neck squamous cell carcinoma (HNSCC) usually include combinations of radiotherapy and surgery, and in some cases addition of chemotherapy. In locally advanced cases cure rates are low. Current prognostic factors cannot foresee the outcome for the individual patient. READ MORE

  4. 4. Molecular heterogeneity of prostate cancer bone metastasis

    Author : Erik Bovinder Ylitalo; Pernilla Wikström; Anders Bergh; Maria Brattsand; Vessela Kristensen; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Prostate cancer; CRPC; castration-resistant; androgen receptor; splice variant; abiraterone; cabazitaxel; ABCB1; cholesterol; Mdr1; P-gp; bone metastasis; immune response; metabolism; osteoblast; osteoclast; BMP; methylation;

    Abstract : Castration-resistant prostate cancer (CRPC) develops after androgen deprivation therapy of advanced PC, often with metastatic growth in bone. Patients with metastatic CRPC have very poor prognosis. Growth of CRPC, in most but not all patients, seems to involve androgen receptor (AR) activity, despite castrate levels of serum testosterone. READ MORE

  5. 5. The Molecular Epidemiology of Non-Small Cell Lung Cancer

    Author : Johan Isaksson; Johan Botling; Eva Brandén; Hirsh Koyi; Aija Knuuttila; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NSCLC; Lung Cancer; Epidemiology; Genetics; KRAS; Pathology; Biomarkers; Oncology; Onkologi;

    Abstract : The aim of this thesis was to explore the role of a spectrum of biomarkers, for disease classification or predictors of treatment outcomes in non-small cell lung cancer (NSCLC).Paper I examined the impact of systemic inflammation on the clinical outcome of NSCLC patients. READ MORE