Search for dissertations about: "triglycerides"

Showing result 1 - 5 of 192 swedish dissertations containing the word triglycerides.

  1. 1. The role of PPARalpha and growth hormone in hepatic lipid metaboism and atherosclerosis

    Author : Anna Ljungberg; Göteborgs universitet; Göteborgs universitet; Gothenburg University; Göteborgs universitet; Gothenburg University; []
    Keywords : ; growth hormone; PPARalpha; atherosclerosis; lipid metabolism; fatty acids; apoB; ADRP; triglycerides; PGC-1; liver;

    Abstract : Dyslipidemia mainly results from oversecretion of apoB-containing lipoproteins from theliver and is one of the most important risk factors for the development of atherosclerosis.Growth hormone (GH) plays a key role in the regulation of lipoprotein metabolism and thus,disturbances in GH secretion are associated with dyslipidemia and cardiovascular disease. READ MORE

  2. 2. Metabolic disturbances in shift workers

    Author : Berndt Karlsson; Giovanni Costa; Umeå universitet; []
    Keywords : shift work; epidemiology; mortality; diabetes; stroke; coronary heart disease; obesity; triglycerides; HDL-cholesterol; insulin; glucose; Occupational and Environmental Medicine; arbets- och miljömedicin;

    Abstract : An increased risk for coronary heart disease among shift workers is earlier shown in the epidemiological literature. The aim of this thesis has been to penetrate metabolic disturbances and obesity among shift workers compared to day workers, and to compare if there are differences in total mortality or cause specific mortality of coronary heart disease (CHD), diabetes or ischaemic stroke in between the two groups. READ MORE

  3. 3. Studies on the assembly of cytosolic lipid droplets. Importance of Phospholipase D and ADRP in the process

    Author : Denis Marchesan; Göteborgs universitet; Göteborgs universitet; Gothenburg University; []
    Keywords : Lipid droplets; triglycerides; caveolin; Phospholipase D PLD ; adipocyte differentiation related protein ADRP ; EGCG;

    Abstract : The storage of triglycerides in cells such as adipocytes, liver or muscle cells is of great physiological importance, having implications for our most important metabolic diseases such as obesity, the metabolic syndrome and type II diabetes. A common denominator in these diseases is the insulin resistance, which is also highly related to the production of atherogenic lipoproteins and the development of atherosclerosis and consequently cardio-vascular diseases. READ MORE

  4. 4. Fatty Acid Composition in Skeletal Muscle : Influence of Physical Activity and Dietary Fat Quality

    Author : Agneta Andersson; Len Storlien; Uppsala universitet; []
    Keywords : Medical sciences; Skeletal muscle; phospholipids; triglycerides; fatty acids; physical activity; lipid peroxidation; dietary fat quality; n-3 polyunsaturated fatty acids; MEDICIN OCH VÅRD; MEDICINE; MEDICIN; Geriatrics; geriatrik;

    Abstract : Insulin sensitivity is related to the fatty acid profile of skeletal muscle. The aim of this thesis was to investigate whether physical activity and dietary fat quality, independent of each other, influence the fatty acid composition of the skeletal muscle lipids. READ MORE

  5. 5. Endogenous and exogenous factors affecting lipoprotein lipase activity

    Author : Mikael Larsson; Gunilla Olivecrona; Aivar Lookene; Ira Tabas; Umeå universitet; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; LPL; APOC1; APOC2; APOC3; ANGPTL4; enzyme inactivation; lipoprotein metabolism; triglycerides; fatty acids; hypertriglyceridemia; CVD; small molecule screening; structure-activity relationship; cardiovascular disease; hjärt- och kärlforskning;

    Abstract : Individuals with high levels of plasma triglycerides are at high risk to develop cardiovascular disease (CVD), currently one of the major causes of death worldwide. Recent epidemiological studies show that loss-of-function mutations in the APOC3 gene lower plasma triglyceride levels and reduce the incidence of coronary artery disease. READ MORE