Search for dissertations about: "trimethylamine N-oxide TMAO"
Found 4 swedish dissertations containing the words trimethylamine N-oxide TMAO.
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1. Polyphenols in Swedish berries and pulses : Characterization and in vivo effects of fractions from lingonberries and brown beans in an Apoe-/- mouse model
Abstract : Consumption of berries and pulses can protect against atherosclerosis and other metabolic diseases, by modulating plasma lipid profile, gut microbiota, and microbiota-dependent metabolites. These nutritional benefits are often attributed to high content of polyphenols (flavonoids and phenolic acids) and dietary fiber. READ MORE
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2. Disease-causing Keratin Mutations and Cytoskeletal Dysfunction in Human Skin : In vitro Models and new Pharmacologic Strategies for Treating Epidermolytic Genodermatoses
Abstract : Epidermolysis bullosa simplex (EBS) and epidermolytic ichthyosis (EI) are rare skin fragility diseases characterized by intra-epidermal blistering due to autosomal dominant-negative mutations in basal (KRT5 or KRT14) and suprabasal (KRT1 or KRT10) keratin genes, respectively. Despite vast knowledge in the disease pathogenesis, the pathomechanisms are not fully understood, and no effective remedies exist. READ MORE
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3. Methods for the Synthesis of PET Tracers and NMR Studies of Ribonuclease A
Abstract : This thesis contains two parts.In the first part, general and versatile palladium-mediated 11C-C bond forming reactions for use in the production of radiotracers for Positron Emission Tomography (PET) were explored. READ MORE
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4. Chronic kidney disease and early vascular ageing : pinpointing culprits of injury and targets for intervention
Abstract : Chronic kidney disease (CKD) is a progressive non-communicable disease, and a clinical model of premature ageing. Approximately 1 in 10 people globally have CKD, defined as abnormalities of kidney structure and/or function that persist for more than threemonths. READ MORE