Search for dissertations about: "trinucleotide threading"

Found 3 swedish dissertations containing the words trinucleotide threading.

  1. 1. Parallel target selection by trinucleotide threading

    University dissertation from Stockholm : KTH

    Author : Pawel Zajac; KTH.; [2009]
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; trinucleotide threading; multiplex amplification; expression profiling; microarray; generic tag; short tandem repeat; microsatellite; electrophoresis; single nucleotide polymorphism; allelotyping; 454; Pyrosequencing; TECHNOLOGY Bioengineering Genetic engineering including functional genomics; TEKNIKVETENSKAP Bioteknik Genteknik inkl. funktionsgenomik;

    Abstract : DNA is the code for all life. Via intermediary RNA the information encoded by the genome is relayed to proteins executing the various functions in a cell. Together, this repertoire of inherently linked biological macromolecules determines all characteristics and features of a cell. READ MORE

  2. 2. Interrogation of Nucleic Acids by Parallel Threading

    University dissertation from Stockholm : KTH

    Author : Erik Pettersson; KTH.; [2007]
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; genotyping; multiplex amplification; trinucleotide threading; single nucleotide polymorphism; genotype calling; Expectation-Maximization; protein-epitope signature tag; expression profiling; Human Protein Atlas; pooled genomic DNA; Pyrosequencing; 454; allelotyping; association studies; bioinformatics; TECHNOLOGY Bioengineering; TEKNIKVETENSKAP Bioteknik;

    Abstract : Advancements in the field of biotechnology are expanding the scientific horizon and a promising era is envisioned with personalized medicine for improved health. The amount of genetic data is growing at an ever-escalating pace due to the availability of novel technologies that allow massively parallel sequencing and whole-genome genotyping, that are supported by the advancements in computer science and information technologies. READ MORE

  3. 3. Methods for Analyzing Genomes

    University dissertation from Stockholm : KTH

    Author : Patrik L. Ståhl; KTH.; [2010]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; array; sequence capture; genotyping; trinucleotide threading; sequencing; massively parallel sequencing; single molecule sequencing; Visual DNA; p53; single nucleotide polymorphism; biomarker; NATURAL SCIENCES Biology Cell and molecular biology Genetics; NATURVETENSKAP Biologi Cell- och molekylärbiologi Genetik;

    Abstract : The human genome reference sequence has given us a two‐dimensional blueprint of our inherited code of life, but we need to employ modern‐day technology to expand our knowledge into a third dimension. Inter‐individual and intra‐individual variation has been shown to be larger than anticipated, and the mode of genetic regulation more complex. READ MORE