Search for dissertations about: "triphosphate"

Showing result 1 - 5 of 80 swedish dissertations containing the word triphosphate.

  1. 1. Cell signalling in cancer. A functional and immunochemical investigation of purinergic,adrenergic, nitrergic, and prostaglandin mediated signalling mechanisms in experimental and human cancer

    Author : Gunnar Nylund; Göteborgs universitet; []
    Keywords : adenosine-5´-triphosphate; colon cancer; extracellular acidification; melanoma; ; microphysiometer; nitric oxide; noradrenaline; prostaglandin E2; sarcoma; tumour cell; metabolism; uridine-5´-triphosphate;

    Abstract : Disturbed cell signalling is a hallmark of the cancer cell, being one important mechanismbehind uncontrolled cell growth. In the current study, we have investigated cancer cellsignalling with the focus on some first messenger and/or their receptors, in the murine celllines, MCG 101, and K1735-M2, and the human colon cancer cell line, HT-29. READ MORE

  2. 2. Impact of Genetic Variants in Inosine Triphosphate Pyrophosphatase and Interferon-λ4 on Natural History, Treatment Response and Ribavirin Pharmacology in Hepatitis C Virus Infection

    Author : Jesper Waldenström; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Hepatitis C virus; HCV; Inosine triphosphate pyrophosphatase; ITPA; interferon-λ4; IFNL4; ribavirin; interferon; PWID; IP-10;

    Abstract : Hepatitis C virus (HCV) impacts on global health with around 70 million chronically infected worldwide. The infection increases the risk of cirrhosis and primary liver cancer. The treatment until 2013 has been based on interferon-α and ribavirin, but is now replaced by direct acting antivirals. READ MORE

  3. 3. Mechanisms for control of nucleoside triphosphate hydrolysis. Effects of DNA and RNA co-factors

    Author : Bertil Macao; Göteborgs universitet; []
    Keywords : ATPase; GTPase; SRP; Ffh; FtsY; SRP RNA; OBP; UL9; oriS; oriS*; HSV-1; helicase.;

    Abstract : In energetically unfavourable biological processes "protein machines" utilize chemical energy from the hydrolysis of high-energy phosphate bonds. Thus, the hydrolysis of a nucleoside triphosphate (NTP) to nucleoside diphosphate (NDP) with the release of free orthophosphate results in a liberation of energy. READ MORE

  4. 4. Studies on the formation of adenosine triphosphate by the cell membrane of human erythrocytes and of tumor cells

    Author : Gunnar Ronquist; Uppsala universitet; []
    Keywords : MEDICINE; MEDICIN;

    Abstract : .... READ MORE

  5. 5. Biochemical and functional studies on ischemically damaged myocardial tissue after administration of phosphoenolpyruvate and adenosine triphosphate early during reperfusion : a study in a paracorporeal rat heart model

    Author : Jan Hultman; Uppsala universitet; []
    Keywords : MEDICINE; MEDICIN;

    Abstract : .... READ MORE