Search for dissertations about: "trophoblast"

Showing result 16 - 20 of 21 swedish dissertations containing the word trophoblast.

  2. 16. Immune regulation at the fetal‐maternal interface with focus on decidual macrophages

    Author : Judit Svensson-Arvelund; Jan Ernerudh; Maria Jenmalm; Göran Berg; Siamon Gordon; Linköpings universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : A successful pregnancy requires that the maternal immune system adapts to tolerate the semi-allogeneic fetal-placental unit. This adaptation mainly occurs locally, i.e. at the fetal-maternal interface, where fetal-derived tissues come into close contact with maternal cells in the uterine endometrium (called decidua during pregnancy). READ MORE

  4. 17. Immune cell composition and cytokine expression in the pregnant and non-pregnant uterus

    Author : Ylva Crona Guterstam; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : The success of implantation and further development of the embryo is heavily dependent on the endometrial immune cell composition and its ability to communicate with fetal semi-allogeneic trophoblast cells. Although our understanding of the immune cell population in the uterus has improved, its precise role in normal reproduction and reproductive disorders is still not fully resolved. READ MORE

  5. 18. Cytokines and immune balance in preeclampsia : a survey of some immunological variables and methods in the study of preeclampsia

    Author : Yvonne Jonsson; Christina Ekerfelt; Göran Berg; Leif Matthiesen; Lucia Mincheva-Nilsson; Linköpings universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Preeclampsia; Cytokines; Leukocytes; Immunology; Placenta; Th1 Th2 balance; Inflammation; Immunobiology; Immunbiologi;

    Abstract : Preeclampsia is one of the most feared pregnancy complications, with a risk of maternal and fetal death and with no ideal therapy readily available. The cause of this strictly pregnancyrelated disease is still unknown and is therefore a great challenge to all researchers in the field of pregnancy-related pathophysiology. READ MORE

  6. 19. Matrix metalloproteinase-26 (MMP-26) and Tissue inhibitor of metalloproteinases-4 (TIMP-4) in normal, hyperplastic, and malignant endometrium

    Author : Radovan Pilka; Lund Obstetrik och gynekologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cancer; Obstetrics; gynaecology; Cytologi; onkologi; cancerology; secretion; Biology; Biologi; Cytology; oncology; implantation; human; endometrium; mRNA; MMP-26; TIMP-4; reproduktion; andrologi; gynekologi; Obstetrik; sexuality; reproduction; sexualitet; andrology;

    Abstract : The aim of the thesis was to study matrix metalloproteinase-26 (MMP-26) and tissue inhibitor of metalloproteinases-4 (TIMP-4) in normal, hyperplastic, and malignant endometrium. Most importantnly, both these molecules may be ivolved in the implantation process. Trophoblast tissue from human as well as mouse embryos produces pro-MMP-9. READ MORE

  7. 20. Immune cells in pregnant uterine mucosa : functional properties, cellular composition and tissue organization

    Author : Lucia Mincheva-Nilsson; Sten Hammarström; Rolf Kiessling; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; immunologically privileged site; TCR γδ cells; CD56 cells; large granular lymphocytes; immunosuppression; cytokine; interleukin; lymphoid cell cluster; intraepithelial lymphocytes; glandular epithelium; immuno electron microscopy; pregnancy; decidua; lactoferrin; lactoferrin receptor; colostrum;

    Abstract : The pregnant uterus mucosa - decidua - is an "immunologically privileged" site. A semiallogeneic embryo is allowed to survive, develop, and grow while the same tissue implanted outside the uterus will be rejected. The decidua basalis, which participates in the placenta formation, is a tissue rich in lymphoid cells. READ MORE