Search for dissertations about: "tropical parasites"

Showing result 1 - 5 of 13 swedish dissertations containing the words tropical parasites.

  2. 1. Structural Studies of Polyamine Biosynthesis Enzymes: Potential Targets for Drugs against Tropical Parasites

    Author : Veronica Tamu Dufe; Biokemi och Strukturbiologi; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; inhibitors; protein crystallography; Molecular biophysics; Molekylär biofysik; tropical parasites; polyamine biosynthesis enzymes;

    Abstract : Two enzymes involved in the biosynthesis of polyamines, ornithine decarboxylase (ODC, from human and Leishmania donovani) and spermidine synthase (SPDS, from Plasmodium falciparum and Caenorhabditis elegans) were studied using biochemical methods, homology modelling and X-ray crystallography. ODC catalyses the first and committed step in polyamine biosynthesis, the decarboxylation of ornithine to putrescine. READ MORE

  4. 2. Immunity and immunological surveillance for malaria elimination in tropical islands

    Author : Zulkarnain Md Idris; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Malaria remains one of the most significant global public health challenges. Nearly half of the world’s population remains at risk, largely in African Region. In the past decade, considerable progress has been made in the global fight to control and eliminate malaria. READ MORE

  5. 3. LIVING WITH PARASITES: AVIAN MALARIA, TELOMERE LENGTH AND LIFE HISTORY TRADE-OFFS

    Author : Asghar Muhammad; MEMEG; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Avian malaria; Plasmodium; qPCR; parasitemia; life history; reproduction; survival; feather growth; MHC; telomere length; heritability; telomere loss; fitness; wild population; Acrocephalus arundinaceus; Delichon urbica;

    Abstract : Haemosporidia is a well-studied group of parasites, which infect mammals, reptiles and birds and use blood sucking vectors for their transmission. By conducting natural population studies and experimental infections, We have been able to detect and quantify Haemosporidia from avian blood to investigate how these pathogens affect their avian hosts. READ MORE

  6. 4. Oral eflornithine treatment of late-stage human African trypanosomiasis

    Author : Mikael Boberg; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Sleeping Sickness; Neglected Tropical Diseases; Enantiomers; Nonlinear Mixed Effects Modeling; Pharmacokinetics; Pharmacodynamics;

    Abstract : Human African trypanosomiasis is a fatal disease unless treated. It is a parasitic vector borne disease endemic in sub-Saharan African countries. Eflornithine is a recommended treatment for gambiense human African trypanosomiasis (g-HAT) in the later disease stage when the parasites have infected the central nervous system. READ MORE

  7. 5. Control or elimination : terms for public health interventions against tungiasis and schistosomiasis haematobium

    Author : Per Nordin; Ingela Krantz; Stig Wall; Andreas Ruppel; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; tungiasis; urogenital schistosomiasis; control; elimination; public health; intervention; diagnosis; treatment; neglected tropical diseases; praziquantel; mass treatment; Public health; folkhälsa;

    Abstract : The thesis revolves around diagnosis and treatment of tungiasis (sand flea disease) and schistosomiasis haematobium. The causing parasites, Tunga penetrans and Schistosoma haematobium, both have the ability to penetrate intact skin. READ MORE