Search for dissertations about: "trpa1"
Showing result 1 - 5 of 10 swedish dissertations containing the word trpa1.
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1. Thermo- and chemosensitive properties of Transient Receptor Potential Ankyrin 1 ion channels
Abstract : The ability to sense and accommodate to an ever-changing environment is crucial for the survival of living organisms. Transient Receptor Potential (TRP) ion channels comprise a large superfamily of cation conducting membrane proteins that function as molecular sensors in diverse sensory processes including perception of light, taste, smell, sound, touch and temperature. READ MORE
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2. Painfully Energetic : A tale of two proteins potentially connected
Abstract : NADH:quinone oxidoreductase (Complex I) is the first enzyme of the respiratory chain and is involved in energy conservation generating an electro-chemical gradient across a membrane. The enzyme can be divided into a membrane spanning domain and a hydrophilic domain, which protrudes from the membrane. READ MORE
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3. Sensory mechanisms in the human upper airway - Role of TRP ion channels
Abstract : The nasal mucosa is richly innervated with sensory nerves having the ability to detect changes in the environment and mediate symptoms such as secretion and itch. Some TRP ion channels such as TRPV1 and TRPA1 are abundantly expressed in sensory nerves and respond to a wide variety of stimuli, including irritants, inflammatory mediators and temperatures. READ MORE
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4. Synthesis of bioactive natural products and analogues
Abstract : Natural products have until recently provided the only remedy for treatment of diseases. The development of modern chemistry in the last centuries has opened the door for tapping into the chemical diversity found in nature. Synthetic natural products, together with analogues, are an important piece in the puzzle towards curing many ailments. READ MORE
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5. Characterization of Membrane Proteins: From a gated plant aquaporin to animal ion channel receptors
Abstract : Membrane proteins play several important roles in a cell. Among these proteins are aquaporins (AQPs) and transient receptor potential (TRP) ion channels that mediate water transport, temperature and noxious chemical sensation, respectively. READ MORE