Search for dissertations about: "truncated models"

Showing result 1 - 5 of 61 swedish dissertations containing the words truncated models.

  2. 1. Estimators of semiparametric truncated and censored regression models

    Author : Maria Karlsson; Thomas Laitila; Göran Broström; Kenneth Carling; Umeå universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Statistics; LTRC; consistency; asymtotic normality; bootstrap; interpurchase intervals; Statistik; Statistics; Statistik; Statistics; statistik;

    Abstract : This thesis contributes in several ways to the existing knowledge on estimation of truncated, censored, and left truncated right censored (LTRC) regression models. Three new semiparametric estimators are proposed, allowing for asymmetric error distributions. READ MORE

  4. 2. Using patient-derived cell models to investigate the role of misfolded SOD1 in ALS

    Author : Elin Forsgren; Jonathan Gilthorpe; Stefan Marklund; Peter Andersen; Thomas Brännström; Ulrika Nordström; Séverine Boillée; Umeå universitet; []
    Keywords : ALS; SOD1; patient-derived models; induced pluripotent stem cells; motor neurons; astrocytes; 20S proteasome low oxygen tension; misfolded SOD1; Neurology; neurologi;

    Abstract : Protein misfolding and aggregation underlie several neurodegenerative proteinopathies including amyotrophic lateral sclerosis (ALS). Superoxide dismutase 1 (SOD1) was the first gene found to be associated with familial ALS. READ MORE

  5. 3. Pharmacometric Methods and Novel Models for Discrete Data

    Author : Elodie L Plan; Mats O Karlsson; Laura Sargentini-Maier; Armel Stockis; Christian Laveille; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmacometrics; pharmacodynamics; disease progression; modelling; discrete data; count; ordered categorical; repeated time-to-event; RTTCE; RCEpT; NONMEM; FOCE; LAPLACE; SAEM; AGQ; pain scores; epilepsy seizures; gastroesophageal symptoms; statistical power; simulations; diagnostics; PHARMACY; FARMACI; Pharmacokinetics and Drug Therapy; Farmakokinetik och läkemedelsterapi;

    Abstract : Pharmacodynamic processes and disease progression are increasingly characterized with pharmacometric models. However, modelling options for discrete-type responses remain limited, although these response variables are commonly encountered clinical endpoints. Types of data defined as discrete data are generally ordinal, e.g. READ MORE

  6. 4. On truncated sequential tests of parameters in various Poisson models with applications to traffic accidents

    Author : Stig Elofsson; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Poisson-fördelning;

    Abstract : .... READ MORE

  7. 5. Bayesian inference for high dimensional factor copula models

    Author : Hoang Nguyen; Maria Conception Ausin Olivera; Pedro Galeano San Miguel; Universidad Carlos III de Madrid; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES;

    Abstract : Copulas have been applied to many research areas as multivariate probability distributions for non-linear dependence structures. However, extending copula functions in high dimensions is challenging due to the increase of model parameters and computational intensity. READ MORE