Search for dissertations about: "tumor markers in breast cancer"
Showing result 1 - 5 of 56 swedish dissertations containing the words tumor markers in breast cancer.
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1. Type IV collagen in breast and colorectal cancer : a potential biomarker of metastatic disease
Abstract : Background: Metastatic colorectal cancer (mCRC) and metastatic breast cancer (mBC) are two leading causes of cancer-related mortality worldwide. Early detection of metastatic disease is critical, and sensitive, easily accessed and cost-effective biomarkers that can diagnose mBC and mCRC at an early stage would have high clinical value. READ MORE
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2. Predictive markers for tamoxifen response in primary breast cancer
Abstract : It is well-known that a majority of breast cancers are hormone-dependent, making endocrine therapy an important adjuvant treatment after surgery. Susceptibility to endocrine treatment is determined by the presence of estrogen receptors (ER) and progesterone receptors (PR) in the tumors. READ MORE
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3. Aspects of Progression in Breast Carcinoma : from ductal carcinoma in situ to invasive cancer
Abstract : In the past decades our knowledge concerning breast cancer progression from ductal carcinoma in situ (DCIS) to invasive cancer has grown rapidly. However, molecular factors driving the progression are still largely unknown. READ MORE
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4. Molecular Analysis of Breast Cancer Transcriptomes, Genomes, and Circulating Tumor DNA
Abstract : Breast cancer is a very heterogeneous disease in terms of clinical characteristics, genetic aberrations and prognosis. In Paper I, we focused on the CD44 molecule that often is aberrantly expressed in breast cancer and is widely used as a marker for cancer stem cells. READ MORE
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5. Genomic Profiling, Mutations and Deranged Signaling in Esophageal Cancer and Hereditary Colorectal Cancer
Abstract : Esophageal cancer and colorectal cancer represents two major types of gastrointestinal tumors. Though refined surgery and introduction of novel chemotherapeutics have improved outcome, more than 2500 Swedes die from these diseases every year. Novel markers for early diagnosis, prognosis and treatment prediction are therefore needed. READ MORE