Search for dissertations about: "tumor necrosis factor-α"

Showing result 1 - 5 of 30 swedish dissertations containing the words tumor necrosis factor-α.

  2. 1. Interleukin 1, tumor necrosis factor α and interleukin 6 in the rat central nervous system : production and effects with particular attention to the fever response

    Author : Silvia Gatti; Stockholms universitet; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neurotoxikologi; Tumörer; Onkologi;

    Abstract : .... READ MORE

  4. 2. Inflammation and lifestyle in cardiovascular medicine

    Author : Jonas Andersson; Kurt Boman; Jan-Håkan Jansson; Lars Johansson; Joep Perk; Umeå universitet; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; C-reactive protein; cardiovascular disease; stroke; atrial fibrillation; lifestyle; interleukin-6; tumor necrosis factor-α; exercise; physical activity; obesity; the metabolic syndrome; fibrinolysis; Cardiology; Kardiologi; Cardiology; kardiologi;

    Abstract : Despite major advances in the treatment and prevention of atherosclerosis the last several decades, cardiovascular disease still accounts for the majority of deaths in Sweden. With the population getting older, more obese and with rising numbers of diabetics, the cardiovascular disease burden may increase further in the future. READ MORE

  5. 3. Exploration of Conditions Affecting Cytokine Production in Experimental Type 1 Diabetes Mellitus

    Author : Lina Thorvaldson; Stellan Sandler; Michael Welsh; Maria Holstad; Maria Faresjö; Uppsala universitet; []
    Keywords : Cell biology; Cytokine; Diabetes; Tumor necrosis factor-α; Interferon-γ; Interleukin-4; Interleukin-10; Transplantation; Pancreatic islet; Glucose; Regulatory T cell; Cellbiologi;

    Abstract : Cytokines are soluble signalling mediators within the immune system, and have been shown to be of importance in the development of type 1 diabetes (T1D). This thesis studied the production of cytokines in experimental models of T1D and during transplantation of insulin-producing islets of Langerhans. READ MORE

  6. 4. Prediction of Alzheimer’s disease in subjects with Mild Cognitive Impairment using biomarkers

    Author : Peder Buchhave; Klinisk minnesforskning; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Alzheimer’s disease; Mild Cognitive Impairment; Biomarkers; Prediction; Cerebrospinal fluid; Amyloid.;

    Abstract : Background: Alzheimer’s disease (AD) is the most common cause of dementia. In order to have effect of future disease-modifying therapies for AD, the disease must be identified early, before the patients have developed dementia. Many patients with Mild Cognitive Impairment (MCI) have prodromal AD, but other causes for the syndrome are common. READ MORE

  7. 5. Islet xenotransplantation : An immunological study in the pig-to-mouse model

    Author : Birgitta Benda; Uppsala universitet; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Oncology; xenotransplantation; porcine; islet; in vivo; knock-out mouse; immunohistochemistry; CsA; MDL 201; 449A; Ig; FcR; IL-6; perforin; granzyme B; macrophage; eosinophilic granulocyte; T cell; TCR; IFN- g; TNF- a; IL-2; Onkologi; Oncology; Onkologi; Clinical Immunology; klinisk immunologi;

    Abstract : Successful clinical xenotransplantation, i.e., transplantation between species, would eliminate the shortage of donor organs. In order to study the acute cellular rejection reaction following discordant xenogeneic transplantation, an experimental pig-to- mouse islet xenotransplantation model was established. READ MORE