Search for dissertations about: "tumor necrosis factor-α"

Showing result 21 - 25 of 38 swedish dissertations containing the words tumor necrosis factor-α.

  2. 21. Studies of pathophysiological mechanisms and oral cavity manifestations in chronic inflammatory diseases

    Author : Guillermo Ruacho Barraza; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Systemic Lupus Erythematosus (SLE) is a chronic autoimmune disease with a 9:1 female predominance where many genetic and clinical characteristics overlap with other inflammatory conditions such as rheumatoid arthritis (RA). Closely monitoring and treating active disease leads to better prognosis and quality of life for these patients since a cure is to date not available. READ MORE

  4. 22. Gene expression profiling in periodontitis

    Author : Haleh Davanian Mohaghegh; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : The chronic inflammatory disease periodontitis is characterized by destruction of periodontal tissue, i.e. the tissues that surround and support the teeth. READ MORE

  5. 23. Effects of immunosuppressive drugs on human adipose tissue metabolism

    Author : Maria J Pereira; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cyclosporin A; tacrolimus; rapamycin; glucocorticoids; new onset diabetes after transplantation; adipocytes; insulin signalling; glucose uptake; lipolysis; lipogenesis;

    Abstract : The immunosuppressive agents (IAs) rapamycin, cyclosporin A and tacrolimus, as well as glucocorticoids are used to prevent rejection of transplanted organs and to treat autoimmune disorders. Despite their desired action on the immune system, these agents have serious long-term metabolic side-effects, including dyslipidemia and new onset diabetes mellitus after transplantation. READ MORE

  6. 24. Studies on the therapeutic modulation of inflammation in the synovial membrane of rheumatoid arthritis

    Author : Petra Neregård; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by inflammation of the synovial membrane that can lead to joint deformity and physical disability. Despite recent progress in the therapeutic field of RA, the exact molecular mechanisms responsible for chronic joint inflammation are not yet completely understood. READ MORE

  7. 25. Adipose markers of metabolic outcome after weight loss

    Author : Daniel Eriksson Hogling; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Adipose tissue is closely linked to metabolic disturbances in obesity. Bariatric surgery such as roux-en-Y gastric bypass (RYGB) remains the most effective treatment of obesity and obesity-related disease. READ MORE