Search for dissertations about: "tumor necrosis factor"

Showing result 21 - 25 of 217 swedish dissertations containing the words tumor necrosis factor.

  2. 21. Vitamin D and Vitamin D-binding Protein in Psoriasis and Effects of Treatment

    Author : Maria Siekkeri Vandikas; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; psoriasis; vitamin D; vitamin D-binding protein; phototherapy; tumor necrosis factor α inhibitor;

    Abstract : Background: Topical vitamin D analogues constitute an established treatment for psoriasis but the role of vitamin D in the pathogenesis of the disease remains controversial. The in loco production and immunomodulatory effects of vitamin D need to be elucidated. READ MORE

  4. 22. Platelet-activating factor, intestinal epithelial cells, and Chron's disease : An experimental study

    Author : Bengt Kald; Linköpings universitet; []
    Keywords : MEDICINE; MEDICIN;

    Abstract : Platelet-activating factor (PAF-acethcr, 1-0-alky l-2-acetyl-s n- glycero-3- phosphocholine), is a potent inflammatory mediator that can be formed by a variety of cells and tissues. In the present investigation, the content of PAFacether was determined in mucosal biopsies from the ileum and colon of patients with Crohn's disease and control patients. READ MORE

  5. 23. Angiogenesis in childhood malignancies

    Author : Erik Sköldenberg; Rolf Christofferson; Göran Läckgren; Agneta Nordenskjöld; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Surgery; Angiogenesis Factor; Biopsy; Needle; Neovascularization; Pathologic; Nephroblastoma; Reference value; Kirurgi; Surgery; Kirurgi; Pediatric Surgery; kirurgi; särskilt barnkirurgi;

    Abstract : Angiogenesis is necessary for the growth and spread of solid tumors. In these studies angiogenesis was measured in childhood malignancies in general and in Wilms’ tumor in particular, and cutting needle biopsy (CNB) specimens were evaluated for diagnosis in childhood renal tumors. READ MORE

  6. 24. Neuropeptides and neurotrophins in arthritis : studies on the human and mouse knee joint

    Author : Ola Grimsholm; Sture Forsgren; Solbritt Rantapää-Dahlqvist; Elvar Theodorsson; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; neuropeptides; neurotrophins; bombesin gastrin-releasing peptide; substance P; brain-derived neurotrophic factor; synovial tissue; knee joint; rheumatoid arthritis; Anatomy; Anatomi;

    Abstract : Neuropeptides, such as substance P (SP) and bombesin/gastrin-releasing peptide (BN/GRP), and neurotrophins are involved in neuro-immunomodulatory processes and have marked trophic, growth-promoting and inflammation-modulating properties. The impact of these modulators in rheumatoid arthritis (RA) is, however, unclear. READ MORE

  7. 25. Effects of aging and inflammatory molecules on the suprachiasmatic circadian clock

    Author : Mikael Nygård; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Circadian; suprachiasmatic; synaptic; inflammation; cytokine; SOCS; interferon; tumor necrosis factor; neuron; firing;

    Abstract : The suprachiasmatic nucleus (SCN) is considered the master circadian pacemaker in the mammalian brain and is vital for generating physiological and behavioral circadian rhythms. During aging and inflammatory conditions the circadian system is frequently affected, but relatively little is known about the mechanisms underlying such effects. READ MORE