Search for dissertations about: "tumor periphery"
Showing result 6 - 10 of 15 swedish dissertations containing the words tumor periphery.
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6. Improving the diagnostic armamentarium of lung cancer
Abstract : Lung cancer is the leading cause of cancer-related death globally, with non-small cell lung cancer (NSCLC) constituting 85% of cases. The introduction of immunotherapies and targeted therapies have dramatically improved the prognosis and outcome for a subset of patients, and stressed the development of diagnostic tools for effective patient selection. READ MORE
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7. Regulatory T cells : molecular and clinical aspects
Abstract : In the immune system’s tug of war with cancer, tolerance mechanisms by which the tumor can control anti-tumor immune responses play a central role in determining the outcome. Regulatory T cells (Treg) induced in the thymus or the periphery, represent one such tolerance mechanism that potentially can be exploited by developing tumors. READ MORE
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8. Getting in and out of shape : relevance for organ formation and cancer
Abstract : A central question during development is how single cells form functional multi-cellular organ structures. The high reproducibility indicates intricate synchronization of cellular behaviors such as migration, proliferation and cell shape changes. READ MORE
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9. Myeloid cells in experimental neuropathologies
Abstract : The first innate immune cells, most importantly for this thesis macrophages, microglia and eosinophils, were described more than 100 years ago and only now do we begin to understand more about their development, functions and properties. So while elimination of pathogens through phagocytosis (macrophages/microglia) or degranulation (eosinophils) were long considered as their main functions, research during the last decades has made it clear that innate immune cells do much more than maintain homeostasis in an organism. READ MORE
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10. Preclinical Molecular Imaging using Multi-Isotope Digital Autoradiography - Techniques and Applications
Abstract : Molecular imaging, both in vivo and ex vivo, is playing an increasingly important role in preclinical medical research. When using radionuclide-labeled tracers, e.g. in the development of radiopharmaceuticals for diagnostic imaging or for radionuclide therapy, quantitative in vivo imaging can be performed using emission tomography. READ MORE