Search for dissertations about: "tumor-associated macrophage TAM"

Showing result 1 - 5 of 7 swedish dissertations containing the words tumor-associated macrophage TAM.

  2. 1. Exploring mechanisms regulating the heterogeneity of tumor-associated macrophages

    Author : Majken Wallerius; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Accumulation of macrophages in the tumor microenvironment is associated to poor prognoses in most human cancers. Tumor-associated macrophages (TAMs) represent a heterogeneous and plastic population of cells that contribute to tumor growth, metastatic dissemination, angiogenesis, and immune suppression. READ MORE

  4. 2. The impact of Wnt5a signaling and tumor associated macrophages in breast cancer

    Author : Catharina Hagerling; Tumörmikromiljö; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Breast cancer; Wnt5a; E-cadherin; B-catenin; migration; invasion; turnor associated macrophages; CD163; CD68; turnor stroma;

    Abstract : Breast cancer is the most common cancer among women worldwide with approximately 1.150.000 new cases each year and accounting for over 400.000 deaths per year. READ MORE

  5. 3. Tumor-associated macrophages and microglia : double-edged sword in tumor evolvement and invasion

    Author : Tatjana Wallmann; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Tumor-associated macrophages (TAMs) are among the most abundant cell types in the tumor microenvironment. TAM infiltration is usually linked to tumor progression, metastasis and poor clinical outcome in most human cancers. READ MORE

  6. 4. The tumor immune microenvironment and clinical outcome in patients with esophageal and gastric adenocarcinoma

    Author : Maria C Svensson; Personlig patologi och cancerbehandling; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medicin och hälsovetenskap; tumor immune microenironment; Esophageal cancer; Gastric cancer; prognosis; Prediction; Adenocarcinoma; T cells; B cells; NK cells; tumor-associated macrophage TAM ; PD-L1; PD-1;

    Abstract : .... READ MORE

  7. 5. Molecular Mechanisms of Action of Histidine-rich Glycoprotein in Angiogenesis Inhibition

    Author : Chunsik Lee; Lena Claesson-Welsh; Jan Palmblad; Uppsala universitet; []
    Keywords : Cell and molecular biology; anti-angiogenesis; angiogenesis inhibitor; endothelial cell; histidine-rich glycoprotein; focal adhesion; tumor-associated macrophages; VEGF; MMP; Cell- och molekylärbiologi;

    Abstract : Angiogenesis, de novo synthesis of blood vessels from the pre-existing vasculature, is required both during embryonic development and in pathophysiological conditions. In particular, tumor growth needs new capillary vessels in order to both deliver oxygen and nutrients and to remove toxin and metabolites. READ MORE