Search for dissertations about: "tumors"

Showing result 11 - 15 of 1169 swedish dissertations containing the word tumors.

  1. 11. Pathogenetic Mechanisms in Soft Tissue Tumors

    Author : Elsa Arbajian; Avdelningen för klinisk genetik; []
    Keywords : Soft tissue tumors; Sarcomas; Gene fusions; SNP array; Next generation sequencing; Haploidization; Point mutations;

    Abstract : Soft tissue tumors (STT) constitute a heterogeneous group of tumors that arise in tissues of mesenchymal origin. They are currently classified according to morphology and resemblance to normal tissue into over 100 subtypes. READ MORE

  2. 12. Morphological Features and Mismatch Repair in Colorectal Tumors

    Author : Britta Halvarsson; Tumörmikromiljö; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Patologi allmän ; patologisk anatomi; Lynch syndrome; Colorectal tumors; HNPCC; Mismatch repaire; pathological anatomy; General pathology; Genetik; cytogenetik; cytogenetics; Genetics; Medicin människa och djur ; Medicine human and vertebrates ; Immunohistochemistry;

    Abstract : Corlorectal cancer affects 5% of individuals in the Western world and heredity is estimated to cause at least 10% of the tumors. Defective mismatch repair (MMR) is a tumorigenic mechanism through which about 15% of colorectal cancer develops and this feature characterizes tumors associated with Hereditary Nonpolyposis Colorectal Cancer (HNPCC) or Lynch syndrome. READ MORE

  3. 13. Intraoperative scintigraphic detection of abdominal endocrine tumors : Development and evaluation of hand held gamma sensitive probes for¹¹¹In

    Author : Ulf Öhrvall; Uppsala universitet; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Surgery; Adrenocortical carcinoma; endocrine pancreatic tumors; mid-gut carcinoids; intraoperative gammadetection; octreotide; scintigraphy; Kirurgi; Surgery; Kirurgi; Surgery; kirurgi;

    Abstract : Surgery of endocrine tumors benefit from accurate pre and- intraoperative localization methods,and scintigraphy has become an important contribution in this respect. In the present thesis therequisites for scintigraphic localization of abdominal endocrine tumors and new detectors forintraoperative gammadetection are evaluated. READ MORE

  4. 14. Genetic characterization of adrenocortical tumors

    Author : Magnus Kjellman; Karolinska Institutet; Karolinska Institutet; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; Adrenocortical tumors; Comparative genomic hybridization; mutation analyzes; in situ hybridization; loss of heterozygosity; MEN 1;

    Abstract : Adrenocortical cancer is a rare tumor form. However, adrenal tumors are today often found incidentally when using imaging techniques on the upper abdomen and should then be investigated. With the advance in molecular understanding of cancer new approaches to manage the disease may become available. READ MORE

  5. 15. Tailoring Radionuclide Therapy of Neuroendocrine Tumors - Bridging the Gaps

    Author : Anna Sundlöv; Tumörmikromiljö; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; 177Lu-DOTATATE; PRRT; somatostatin analogs; pituitary function; renal function; dosimetry; 68Ga-DOTATATE; individualized treatment; neuroendocrine tumors;

    Abstract : Background and Aims: Radionuclide therapy is systemic, targeted radiotherapy. As such, we can apply the basic principles of radiobiology used in everyday practice in radiation oncology, as a means of tailoring the treatment to each patient and optimizing the balance between efficacy and toxicity. READ MORE