Search for dissertations about: "tumour development"

Showing result 1 - 5 of 297 swedish dissertations containing the words tumour development.

  2. 1. Laparoscopy and tumour growth : a clinical and experimental study

    Author : Owe Lundberg; Anders Kristoffersson; Dag Arvidsson; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Surgery; laparoscopy; tumour growth; metastases; gallbladder cancer; pneumoperitoneum; blood flow; Kirurgi; Surgery; Kirurgi; kirurgi; Surgery;

    Abstract : Background and aims: Laparoscopic technique was quickly adopted in general surgery because of less pain, quicker recovery and shorter hospital stay. In the 1990´s several reports on port site metastases restrained the enthusiasm to use laparoscopic surgery in malignant diseases. READ MORE

  4. 2. Microenvironmental Impact on Tumour Cell Phenotype and Genotype in Adult and Paediatric Tumours

    Author : Hiroaki Yasui; Avdelningen för klinisk genetik; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cancer genotype; cancer phenotype; malignant rhabdoid tumour; neuroblastoma; ovarian cancer; tumour evolution; Wilms tumour;

    Abstract : This thesis explores how the tumour microenvironment affects the phenotype and shapes the evolution of cancer cells. It encompasses four separate studies:First, we explored the effect of chemokines on the peritotumoral microenvironment of ovarian cancer. READ MORE

  5. 3. Computational Analysis of Tumour Heterogeneity

    Author : Stefanie Friedrich; Erik Sonnhammer; Martin Hemberg; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; tumour heterogeneity; human genome and gene expression analyses; pathway annotation; fusion transcript detection; copy number calling; and high-resolution data; Biochemistry towards Bioinformatics; biokemi med inriktning mot bioinformatik;

    Abstract : Every tumour is unique and characterised by its genetic, epigenetic, phenotypic, and morphological signature. The diversity observed between and within tumours, and over time, is termed tumour heterogeneity. An increased heterogeneity within a tumour correlates with cancer progression, higher resistance rates, and poorer outcome. READ MORE

  6. 4. Multiparametric MRI for evaluation of tumour treatment response : Studies of 177Lu-octreotate therapy of neuroendocrine tumour

    Author : Mikael Montelius; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cancer; Functional imaging; IVIM; MRI; DWI; DCE; histology; 177Lu-octreotate; small intestine neuroendocrine tumour; NET; diffusion; perfusion; semi-quantitative; proteomics; ionizing radiation; biology; imaging biomarker;

    Abstract : Clinical assessment of tumour response to treatment largely relies on estimates of tumour size by, e.g., measuring the largest tumour diameters on magnetic resonance (MR) or computed tomography (CT) images, weeks or months after treatment. READ MORE

  7. 5. Small intestinal neuroendocrine tumours - Disease models, tumour development, and remedy

    Author : Tobias Hofving; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; neuroendocrine tumours; tumour models; SMAD4; 177Lu-octreotate therapy; immunotherapy;

    Abstract : Small intestinal neuroendocrine tumours (SINETs) are malignant neoplasms which at the time of diagnosis often present with distant metastasis. The field of SINET research faces several challenges. READ MORE