Search for dissertations about: "tumour"

Showing result 6 - 10 of 1016 swedish dissertations containing the word tumour.

  2. 6. Multiparametric MRI for evaluation of tumour treatment response : Studies of 177Lu-octreotate therapy of neuroendocrine tumour

    Author : Mikael Montelius; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cancer; Functional imaging; IVIM; MRI; DWI; DCE; histology; 177Lu-octreotate; small intestine neuroendocrine tumour; NET; diffusion; perfusion; semi-quantitative; proteomics; ionizing radiation; biology; imaging biomarker;

    Abstract : Clinical assessment of tumour response to treatment largely relies on estimates of tumour size by, e.g., measuring the largest tumour diameters on magnetic resonance (MR) or computed tomography (CT) images, weeks or months after treatment. READ MORE

  4. 7. Computational Analysis of Tumour Heterogeneity

    Author : Stefanie Friedrich; Erik Sonnhammer; Martin Hemberg; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; tumour heterogeneity; human genome and gene expression analyses; pathway annotation; fusion transcript detection; copy number calling; and high-resolution data; Biochemistry towards Bioinformatics; biokemi med inriktning mot bioinformatik;

    Abstract : Every tumour is unique and characterised by its genetic, epigenetic, phenotypic, and morphological signature. The diversity observed between and within tumours, and over time, is termed tumour heterogeneity. An increased heterogeneity within a tumour correlates with cancer progression, higher resistance rates, and poorer outcome. READ MORE

  5. 8. Stromal collagens in colorectal cancer and in colorectal liver metastases : tumour biological implications and a source for novel tumour markers

    Author : Hanna Nyström; Malin Sund; Peter Naredi; Per Sandström; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Colorectal cancer; colorectal liver metastases; tumour marker; stroma; type IV collagen; metastatic growth pattern; kirurgi; Surgery;

    Abstract : Background: Colorectal cancer (CRC) remains one of the leading causes of cancer-related mortality. About 50 % of patients with CRC will develop subsequent liver metastases (CLM). The survival for untreated CLM is only a few months and liver resection provides the only chance for a lasting cure. READ MORE

  6. 9. Characteristics of tumour markers CEA, CA 50 and CA 242 in serum with reference to colorectal cancer

    Author : Boel Engarås; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Tumour; CEA; CA 50; CA 242; colorectal cancer; follow-up;

    Abstract : There is no consensus on if and how to conduct colorectal cancer surveillance. Serum levels of tumour markers and especially CEA increase before a recurrence is detected by clinical diagnosis. Second look surgery based on elevated serum levels of CEA has been beneficial for individual patients. READ MORE

  7. 10. Aspects of Tumour Targeting : Preclinical Studies on Human Malignant Cells in vitro

    Author : Maria Dahlström Wester; Annelie Lindström; Åke Wasteson; Lars Gedda; Linköpings universitet; []
    Keywords : MEDICINE; MEDICIN;

    Abstract : Exclusive eradication of tumour cells causing minimal damage to healthy tissue, a concept referred to as targeting, is an interesting approach to improve the outcome for patients afflicted with cancer.The general aim of this thesis was to highlighten aspects that could be of importance in developing novel treatment regimens based on specific targeting of tumour cells. READ MORE