Search for dissertations about: "tunicamycin."

Showing result 1 - 5 of 10 swedish dissertations containing the word tunicamycin..

  1. 1. Structural and Functional Studies of Membrane Proteins For Future Development of Antimicrobial Drugs

    Author : Elin Dunevall; Göteborgs universitet; Göteborgs universitet; Gothenburg University; []
    Keywords : Sialic acid transporters; SiaT; MraY; Tunicamycin; Antibiotic resistance;

    Abstract : Antibiotic resistance is a world-wide occurring problem which threatens human health. Without development of any new and effective antibiotics, the rapid growth of antibiotic-resistant bacterial infections could put society in a situation resembling the pre-antibiotic era when a simple lung infection could kill a human being. READ MORE

  2. 2. Plant Calreticulins - isoforms, localization and function

    Author : Karin Svensson; Biologiska institutionen; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; arabidopsis thaliana; calcium; isoform; endoplasmic reticulum; chaperone; tunicamycin;

    Abstract : Calreticulin (CRT) is an endoplasmic reticulum (ER)-located protein involved in quality control of newly synthesized proteins as well as in calcium homeostasis of the cell. Most of what is known about CRT arises from studies of mammalian systems. READ MORE

  3. 3. Studies on N-linked glycosylation in proliferation and viability of normal and tumor cells in vitro

    Author : Magdalena Carlberg; Karolinska Institutet; Karolinska Institutet; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; Apoptosis; DNA synthesis; IGF-1 receptor; HMG-CoA reductase; lovastatin; mevalonate; N-linked glycosylation; PDGF; SV40-transformation; tumor; tunicamycin.;

    Abstract : STUDIES ON N-LINKED GLYCOSYLATION IN PROLIFERATION ANDVIABILITY OF NORMAL AND TUMOR CELLS IN VITROby Magdnlena CarlbergUnit of Tumor Pathology, Department of Oncology and Pathology, Karolinska Institute,S-l 71 77 Stockholm, Sweden.A number of studies suggest a critical role of N-linked glycosylation for cellularproliferation. READ MORE

  4. 4. Role of dolichyl phosphate, N-linked glycosylation and cell membrane expression of insulin-like growth factor-1 receptor in maintenance of malignant cell growth

    Author : Anica Dricu; Karolinska Institutet; Karolinska Institutet; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP;

    Abstract : ROLE OF DOLICHYL PHOSPHATE, N-LINKED GLYCOSYLATION AND CELLMEMBRANE EXPRESSION OF INSULIN-LIKE GROWTH FACTOR-1 RECEPTOR IN MAINTENANCE OF MALIGNANTCELL GROWTH Several studies have demonstrated that mevalonate (MVA) synthesis is requiredfor cell proliferation. The mechanisms underlying MVA-regulated cell growth are stillnot fully understood. READ MORE

  5. 5. Plant Calreticulins -Calcium-binding proteins with many functions

    Author : Anna Christensen; Biokemi och Strukturbiologi; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; tobacco; plant; calreticulin; isoforms; Arabidopsis; localization; mouse embryonic fibroblasts;

    Abstract : Endoplasmic reticulum (ER) plays an important role in protein synthesis, folding, maturation and transport of newly synthesized proteins, as well as the regulation of cellular Ca2+ homeostasis. A protein that is involved in several of these functions in the ER is calreticulin (CRT), which is a Ca2+-binding chaperone that resides in the lumen of the ER. READ MORE