Search for dissertations about: "twins gestation"

Found 4 swedish dissertations containing the words twins gestation.

  1. 1. Does cancer originate in utero?

    Author : Magnus Kaijser; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Epidemiology; prenatal exposure delayed effects; breast neoplasms; testicular neoplasms; lung neoplasms; pregnancy; estrogens; estriol; low birth weight body weight; height; twins; matemal exposure; smoking; infant premature; small for gestational age.;

    Abstract : The purpose of the present thesis was to evaluate Trichopoulos' hypothesis that breast cancer can originate in utero, and to examine the role of antenatal estrogen exposure in the etiology of testicular cancer. First, we used data from a Swedish-Norwegian cohort study on risk factors for small-for-gestational-age births to identify markers for antenatal estrogen exposure. READ MORE

  2. 2. Exposures in utero and chronic disease : an alternative methodological approach

    Author : Anna Hübinette; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Cardiovascular disease; acute myocardial infarction; angina pectoris; breast neoplasms; birth weight; birth anthropometrics; twin study; epidemiology; etiology; risk factors; insulin-like growth factors; preeclampsia; longitudinal study.;

    Abstract : The aims of this thesis were to evaluate maternal and birth characteristics as risk factors for breast cancer and cardiovascular disease later in life, and to assess maternal serum concentrations of insulin-like growth factors in pregnancies complicated by preeclampsia. Birth characteristics and risks of breast cancer were studied in a case-control study nested within the population-based Swedish Twin Register (Paper 1). READ MORE

  3. 3. Fetal programming and subsequent risks in adulthood : are the associations confounded by genetic and/or environmental factors?

    Author : Niklas Bergvall; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : The fetal origins hypothesis proposes that fetal growth is inversely associated with subsequent adult disease risk. The objective of this thesis was to investigate whether familial (shared environmental and genetic) factors confound the association between birth weight and risks of hypertension, low intellectual performance, and type-2 diabetes. READ MORE

  4. 4. Very preterm birth : etiological aspects and short and long term outcomes

    Author : Stefan Johansson; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Very preterm birth, occurring before 32 completed weeks of gestation, is an often unexplained pregnancy complication affecting approximately 1 to 2 percent of all births. This thesis includes four studies regarding the etiology, and short and long term outcomes of very preterm birth, using Swedish population-based data. READ MORE