Search for dissertations about: "type 2 diabetes and obesity 2001"

Showing result 1 - 5 of 9 swedish dissertations containing the words type 2 diabetes and obesity 2001.

  2. 1. Genetics of type 2 diabetes and the metabolic syndrome

    Author : Mia Klannemark; Malmö Institutionen för kliniska vetenskaper; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; diabetology; secreting systems; Endocrinology; PDE3B; PPARG; LPL; metabolic syndrome; diabetes; genetic; HSL; UCP2; Endokrinologi; sekretion; diabetologi;

    Abstract : Type 2 diabetes and the metabolic syndrome are highly prevalent disorders with severe complications such as cardiovascular disease. The aetiology of type 2 diabetes and the metabolic syndrome is not known, but the interaction between genetic factors and environmental triggers is important. READ MORE

  4. 2. Genes implicated in the development of obesity and obesity-related disease

    Author : Kajsa Lindell; Göteborgs universitet; []
    Keywords : obesity; adipose tissue; hypothalamus; leptin; leptin receptor; 5 untranslated region; hypertension; angiotensinogen; DNA microarray;

    Abstract : Obesity is a major health problem because of its dramatic increase in prevalence and the association of obesity with type 2 diabetes, coronary heart disease, hypertension and stroke. Although mutations in certain genes have been shown to cause obesity, the molecular mechanisms underlying obesity and obesity-related disease are still largely unknown. READ MORE

  5. 3. Stress system function in abdominal obesity. The hypothalamic-pituitary-adrenal axis and the sympathetic nervous system in middle-aged men

    Author : Thomas Ljung; Göteborgs universitet; []
    Keywords : Abdominal obesity; stress; HPA axis; cortisol; glucocorticoid receptors; sympathetic nervous system; catecholamines; depression; SSRI;

    Abstract : Background: There is a strong relationship between central (abdominal, visceral) obesity, impaired glucose tolerance, insulin resistance, dyslipidemia and elevated blood pressure. These abnormalities are included in the term Metabolic Syndrome, and indicate an elevated risk for cardiovascular disease and diabetes type 2. READ MORE

  6. 4. Common risk factors associated with acute myocardial infarction: Population-based studies with a focus on gender differences

    Author : Charlotte A Larsson; Samhällsmedicin; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cortisol; insulin resistance; abdominal obesity; hypertension; type 2 diabetes; population-based; AMI; gender differences; physical activity; left ventricular hypertrophy;

    Abstract : The overall aim of this thesis was to explore how the risk for AMI, and the associations between several of its risk factors, differs by gender. Information was collected from four Swedish cohorts: one patient cohort from Skara (1992-1993, n=1149) and three population-based cohorts, i.e. READ MORE

  7. 5. The Role of Phosphodiesterase 3B in the Regulation of Insulin Secretion

    Author : Linda Härndahl; Institutionen för experimentell medicinsk vetenskap; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; diabetology; Endokrinologi; sekretion; diabetologi; secreting systems; Endocrinology; beta-cell; diabetes; islet; PDE3B; cAMP;

    Abstract : Pancreatic beta-cell dysfunction and insulin resistance are the two hallmarks of type 2 diabetes. An early sign of beta-cell dysfunction is impaired nutrient-induced insulin release. Several insulin secretagogues act by increasing the formation of intracellular cAMP. READ MORE