Search for dissertations about: "type 2 diabetes mellitus"

Showing result 11 - 15 of 234 swedish dissertations containing the words type 2 diabetes mellitus.

  1. 11. Search for Type 2 Diabetes Susceptibility Genes Using Multiple Approaches

    University dissertation from Cecilia Lindgren, UMAS ing. 46, 205 02 Malmö, Sweden

    Author : Cecilia Lindgren; Lund University.; Lunds universitet.; [2002]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; single nucleotide polymorphism SNP ; transmission-disequilibrium test TDT ; genetic variation; single strand conformational polymorphism SSCP ; gene expression; insulin; glucose; genome-wide scan; linkage; genetic association; Type 2 diabetes; early onset diabetes EOD ; sekretion; diabetologi; Endokrinologi; diabetology; Endocrinology; secreting systems; signal-to-noise ratio SNR ;

    Abstract : Type 2 diabetes mellitus is a multifactorial disorder characterized by chronic hyperglycemia resulting from pancreatic dysfunction and insulin resistance. It is a common disorder with a complex pattern of inheritance, likely to reflect the influence of multiple genetic and environmental factors on the diabetes risk. READ MORE

  2. 12. The Diabetes Incidence Study in Sweden (DISS): Ascertainment, risk factors, and problems with classification

    University dissertation from Bengt Littorin, Södervärns Vårdcentral, Ahlmansgatan 12, S-214 27 Malmö, Sweden

    Author : Bengt Littorin; Lund University.; Lunds universitet.; [2001]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; type 1; stress; register; life events; incidence; ICA; family characteristics; GADA; epidemiology; diabetes mellitus; classification; Ascertainment; BMI; type 2; unclassifiable; year of diagnosis.; Endocrinology; secreting systems; diabetology; Endokrinologi; sekretion; diabetologi;

    Abstract : The Diabetes Incidence Study in Sweden (DISS) registers diabetes in young adults aged 15-34 years in Sweden. This thesis aims to validate the ascertainment, methods in the classification of diabetes, and putative etiological factors such as family background, psychological stress, and BMI, that may affect the incidence of diabetes in young adults, in the DISS registry. READ MORE

  3. 13. Integrating bioinformatics and physiology to describe genetic effects in complex polygenic diseases

    University dissertation from Department of Clinical Sciences, Lund University

    Author : Hemang Parikh; Lund University.; Lunds universitet.; [2009]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Insulin sensitivity; Type 2 diabetes mellitus; Skeletal muscle; Gene expressionprofiling; TXNIP; Maximal oxygen uptake; Type 1 fibers; NDUFB5; CPT1B; ATP5C1; AHNAK; CAST; Genome-wide association studies.;

    Abstract : Type 2 diabetes mellitus (T2DM) results from interaction between genetic and environmental factors. The worldwide prevalence of T2DM is increasing rapidly due to reduction in physical activity, increase in dietary intake, and the aging of the population. READ MORE

  4. 14. Control of metabolism and hormone secretion from pancreatic alpha and beta cells

    University dissertation from Molecular Metabolism

    Author : Jelena Stamenkovic; Lund University.; Lunds universitet.; Lund University.; Lunds universitet.; [2014]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; CLOCK genes; insulin; glucagon; metabolites; mitochondria; knock out;

    Abstract : Type 2 Diabetes (T2D) is a multifactorial disease, which has made it difficult to resolve its pathophysiology. We investigated processes that could contribute to the development of T2D. READ MORE

  5. 15. Diabetes Mellitus at the Time for Diagnosis Studies on Prognostic Factors

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Mats Martinell; Uppsala universitet.; [2017]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; New-onset Diabetes Mellitus; socioeconomic position; epidemiology; diabetes complications; diabetic retinopathy; cellular immunology; diabetes classification; type 2 diabetes; latent autoimmune diabetes in adults LADA ; type 1 diabetes; Allmänmedicin; Family Medicine; Endokrinologi och Diabetologi; Endocrinology and Diabetology;

    Abstract : The aim for this thesis was to identify prognostic factors for chronic diabetes complications that exist at the time of diabetes diagnosis.Low level of education (<12 years) and low income (<60% of median) was found to increase the risk to have high (>70 mmol/mol) HbA1c at the time of diagnosis with 34 % and 35 %, respectively. READ MORE