Search for dissertations about: "type 2 diabetes mellitus"
Showing result 16 - 20 of 278 swedish dissertations containing the words type 2 diabetes mellitus.
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16. Mechanisms by which variants in the TCF7L2 gene increase the risk of developing Type 2 diabetes
Abstract : Type 2 diabetes mellitus (T2DM) is a heterogeneous disease with a multifactorial aetiology comprising of genetic and environmental factors. The common variant most highly associated with T2DM known to date is a SNP rs7903146 in the TCF7L2 gene. However, the role TCF7L2 plays in the development of T2DM was unclear. READ MORE
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17. Semi-mechanistic models of glucose homeostasis and disease progression in type 2 diabetes
Abstract : Type 2 diabetes mellitus (T2DM) is a metabolic disorder characterized by consistently high blood glucose, resulting from a combination of insulin resistance and reduced capacity of β-cells to secret insulin. While the exact causes of T2DM is yet unknown, obesity is known to be a major risk factor as well as co-morbidity for T2DM. READ MORE
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18. Pharmacoepidemiologic Studies of Diabetes Mellitus - with special reference to - Glucose Control and Prognosis of Type 2 Diabetes
Abstract : The efficacy and safety of antihyperglycaemic drugs have been evaluated in one American and one British randomized clinical trial, which have given contradictory results. The positive results of the latter may be more convincing as it included a greater number of patients and as its duration was longer. READ MORE
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19. Common variants in genes regulating free fatty acid metabolism and risk of type 2 diabetes and cardiovascular disease
Abstract : Abstract The present study evaluated genetic and metabolic factors influencing the risk for type 2 diabetes and cardiovascular disease (CVD) with special reference to increased concentrations of free fatty acids (FFA) in 1174 Swedish diabetic and nondiabetic subjects. Common polymorphisms in the fatty acid binding protein 2 (FABP2), the B2-adrenergic receptor (B2-AR), the B3 -adrenergic receptor (B3-AR) and the uncoupling protein 1 (UCP-1) genes were related to anthropometric and metabolic variables. READ MORE
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20. Oral Health and Diabetes : Studies on health and oral self-care in subjects with type 2 diabetes
Abstract : Oral manifestations have been reported as risk factors for diabetes mellitus, but diabetes has also attracted the attention as part of the influence on oral disease. The aims of this thesis were to evaluate several aspects of oral health among type 2 diabetic subjects in relation to various diabetes-related variables and to health-related quality of life (HRQL). READ MORE