Search for dissertations about: "ulf gyllensten"

Showing result 1 - 5 of 23 swedish dissertations containing the words ulf gyllensten.

  2. 1. Biochemical genetic variation, intraspecific genetic structure and postglacial evolution of select north European vertebrate species

    Author : Ulf Gyllensten; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Evolution biologi ; Populationsgenetik;

    Abstract : Analysis of the tempo and mode of intraspecific differentiation provides important information for understanding subspeciation, for construction of taxonomic hierarchies within a species and for management of genetic variation in natural populations.The present thesis describes the genetic structure of natural populations of willow grouse (Lagopus tagopus L. READ MORE

  4. 2. Self-sampling for HPV testing in primary cervical screening : Including clinical and health economic aspects

    Author : Riina Aarnio; Matts Olovsson; Ulf B. Gyllensten; Ingrid Wikström; Christer Borgfeldt; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; HPV; self-sampling; cervical screening; CIN2 ; cost-effectiveness; Obstetrik och gynekologi; Obstetrics and Gynaecology;

    Abstract : Persistent infection with high-risk human papillomavirus (HPV) is a prerequisite for the development of cervical cancer. HPV testing has higher sensitivity for high-grade cervical intraepithelial neoplasia (CIN2+) than cytology, resulting in more effective screening. READ MORE

  5. 3. Sensitive Forensic DNA Analysis : Application of Pyrosequencing and Real-time PCR Quantification

    Author : Hanna Andréasson; Marie Allen; Ulf Gyllensten; Pål Nyrén; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Genetics; forensic; sensitive DNA analysis; DNA quantification; mtDNA; Real-time PCR; Pyrosequencing; Genetik; Clinical genetics; Klinisk genetik;

    Abstract : The field of forensic genetics is growing fast and the development and optimisation of more sensitive, faster and more discriminating forensic DNA analysis methods is highly important. In this thesis, an evaluation of the use of novel DNA technologies and the development of specific applications for use in forensic casework investigations are presented. READ MORE

  6. 4. Identification and clinical implementation of biomarkers for cervical cancer

    Author : Malin Berggrund; Ulf Gyllensten; Stefan Enroth; Matts Olovsson; Pär Sparén; Uppsala universitet; []
    Keywords : Cervical cancer; Human papilloma virus; Screening; Self-sampling; Biomarkers; Vaginal microbiota; Medicinsk vetenskap; Medical Science;

    Abstract : Introduction of organised screening programs and prophylactic vaccination against human papilloma virus (HPV) have successfully reduced the incidence of cervical cancer globally. In Sweden, the incidence has been reduced by about 50 % since the introduction of the national screening programme in the late 1960’s. READ MORE

  7. 5. Dissecting the Genetic Basis of Systemic Lupus Erythematosus : The Pursuit of Functional Variants

    Author : Angélica María Delgado Vega; Ulf Gyllensten; Marta E. Alarcon-Riquelme; Jane Worthington; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Systemic Lupus Erythematosus; SLE; Genetic Mapping; Association Studies; Functional Variants; TNFSF4; STAT4; IRF5; CD226; BLK; BANK1; Systemisk Lupus Erythematosus; SLE; Genetik; Genetisk Association; Funktionella Varianter; TNFSF4; STAT4; IRF5; CD226; BLK; BANK1; Lupus Eritematoso Sistémico; LES; Estudios de Asociación Genética; Variantes Funcionales; TNFSF4; STAT4; IRF5; CD226; BLK; BANK1; Medical Genetics; Medicinsk genetik; Medical Science; Medicinsk vetenskap;

    Abstract : Systemic lupus erythematosus (SLE) is a chronic and systemic autoimmune disease that primarily affects women during the childbearing years. SLE is characterized by the production of autoantibodies against nucleic acids and their interacting proteins. READ MORE