Search for dissertations about: "uncoupling protein"

Showing result 1 - 5 of 47 swedish dissertations containing the words uncoupling protein.

  1. 1. Uncoupling Proteins Regulation by IGF-1 and Neuroprotection during Hyperglycemia in Vitro

    University dissertation from Stockholm : Institutionen för neurokemi

    Author : Helena Gustafsson; Anna Forsby; David Tomlinson; [2004]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; uncoupling protein; oxidative stress; diabetes; neuropathy; SH-SY5Y; NATURAL SCIENCES Biology Cell and molecular biology Neurobiology; NATURVETENSKAP Biologi Cell- och molekylärbiologi Neurobiologi;

    Abstract : Diabetic neuropathy is believed to arise due to oxidative stress following hyperglycemic situations. Uncoupling proteins (UCPs) constitute a subgroup of mitochondrial transporter proteins with putative antioxidant properties. READ MORE

  2. 2. Protein folding without loops and charges

    University dissertation from Stockholm : Department of Biochemistry and Biophysics, Stockholm University

    Author : Martin Kurnik; Mikael Oliveberg; Kevin W. Plaxco; [2012]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; protein folding; folding cooperativity; protein aggregation; protein charges; protein engineering; biokemi; Biochemistry;

    Abstract : Going down the folding funnel, proteins may sample a wide variety of conformations, some being outright detrimental to the organism. Yet, the vast majority of polypeptide molecules avoid such pitfalls. Not only do they reach the native minimum of the energy landscape; they do so via blazingly fast, biased, routes. READ MORE

  3. 3. The Role of Mitochondrial Uncoupling in the Development of Diabetic Nephropathy

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Malou Friederich Persson; Fredrik Palm; Richard K. Porter; [2012]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Kidney; mitochondria; Uncoupling Protein-2; Adenosine Nucleotide Transporter; uncoupling; diabetes; diabetic nephropathy; db db; dinitrophenol; Coenzyme Q10; oxygen; rats; mice; Physiology; Fysiologi; Medical Cell Biology; Medicinsk cellbiologi;

    Abstract : Diabetes is closely associated with increased oxidative stress, especially originating from the mitochondria. A mechanism to reduce increased mitochondria superoxide production is to reduce the mitochondria membrane potential by releasing protons across the mitochondria membrane. READ MORE

  4. 4. On protein oxidation, lifespan and aging in Saccharomyces cerevisiae

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Hugo Aguilaniu; [2003]
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; asymmetric cell division; protein oxidation; yeast; aging; signalling pathways;

    Abstract : In this thesis, we have investigated the physiology of protein oxidation and its possible role in the aging of the yeast Saccharomyces cerevisiae. There are two ways to measure yeast aging. First, they can only divide a finite number of times even when all nutrients necessary for division are provided. This is replicative aging. READ MORE

  5. 5. Enterostatin - target proteins and intracellular mechanisms. Function in food intake and energy metabolism

    University dissertation from Karin Berger, BMC B11, 221 84 Lund, Sweden

    Author : Karin Berger; [2003]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; ATP; energy metabolism; insulin; uncoupling protein; beta-casomorphin; opiate; SK-N-MC; INS-1; Medicin människa och djur ; Medicine human and vertebrates ; fat intake; F1F0-ATP synthase; appetite; enterostatin; satiety; obesity;

    Abstract : Hunger and satiety are the results of complex neural events that involve several neurotransmitters and peptides. Enterostatin is an appetite-regulating peptide released in the intestine in response to fat ingestion. Enterostatin specifically decreases fat intake, but has also metabolic effects like inhibition of insulin secretion. READ MORE