Search for dissertations about: "uncoupling protein"
Showing result 16 - 20 of 52 swedish dissertations containing the words uncoupling protein.
-
16. Mechanisms of apoptosis induced by a protein complex isolated from human milk : with focus on the role of mitochondria
Abstract : Human milk contains a protein complex comprising of a folding variant of human alpha-lactalbumin and oleic acid (C18:1). Both, a milk fraction containing this complex (MAL, for multimeric (alpha- lactalbumin). READ MORE
-
17. Oxygen Metabolism in Experimental Kidney Disease
Abstract : Tubulointerstitial hypoxia has been proposed a unifying mechanism behind the development of chronic kidney disease (CKD), regardless of primary diagnosis. Important factors that contribute to the development of hypoxia are reduced bioavailability of nitric oxide (NO), oxidative stress and mitochondria uncoupling. READ MORE
-
18. The pathophysiology of respiratory chain dysfunction
Abstract : Mutations of mitochondrial DNA cause a variety of clinical syndromes. It is unclear whether impaired oxidative phosphorylation on its own is the main cause of pathology or whether other factors such as secondary metabolic alterations, enhanced formation of reactive oxygen species (ROS) and induction of apoptosis also may contribute to the clinical phenotype. READ MORE
-
19. Insulin resistance in pancreatic cancer
Abstract : The dismal prognosis of pancreatic cancer (PC) is related to metabolic complications of the tumor. Impaired glucose tolerance or diabetes due to insulin resistance, and cachexia are observed early and frequently in these patients. The basic mechanisms of PC-associated insulin resistance and weight loss are not fully understood. READ MORE
-
20. Insulin action and secretion after surgical trauma : an experimental study in the rat
Abstract : Physical injury or surgical trauma leads to an endocrine-metabolic response that causes a catabolic state designed to promote the healing process. Insulin resistance and mobilization of endogenous fuel stores are prominent changes in metabolism seen after surgery. READ MORE