Search for dissertations about: "unrelated donor"

Showing result 1 - 5 of 27 swedish dissertations containing the words unrelated donor.

2. 1. Allogeneic stem cell transplantation : patients’ and sibling donors’ perspectives

   Author : Annika M Kisch; Malmö högskola; []
   Keywords : Allogeneic haematopoietic stem cell transplantation; Confidentiality; Information and care model; Quality of life; Perspectives; Sibling donor; Stem cell donation;

   Abstract : Allogeneic haematopoietic stem cell transplantation (hereafter HSCT) is an established treatment which offers a potential cure for a variety of diseases, mainly haematological malignancies. However, the treatment is also associated with significant risks of acute complications and late side effects, including mortality. READ MORE

4. 2. HLA polymorphism : genomic typing and impact on unrelated stem cell transplantation

   Author : Anna Aldener-Cannavá; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : The HLA (Human Leukocyte Antigen) region is the most polymorphic in the human genome. The extended polymorphism contributes to the ability both of individuals and populations to combat diversity in the pathogens to which they are exposed. READ MORE

5. 3. Potential Hazards for Haematopoietic Stem Cell Donors

   Author : Simon Pahnke; Hans Hägglund; Gunnar Larfors; Nina Worel; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; stem cell donor; stem cell transplantation; cancer; haematology; Medicinsk vetenskap; Medical Science;

   Abstract : The aim of this thesis has been to increase our knowledge about the allogeneic stem cell donation procedure and the associated risks for stem cell donors.  In a first study (paper I), we described the donation procedure and short-term side effects of 1957 donors included in the Nordic Register of Haematopoietic Stem Cell Donors. READ MORE

6. 4. HLA and KIR gene polymorphism in hematopoietic stem cell transplantation

   Author : Marie Schaffer; Karolinska Institutet; Karolinska Institutet; []
   Keywords : HLA; KIR; NK cells; hematopoietic stem cell transplantation; unrelated donor;

   Abstract : The major histocompatibility complex (MHC) in humans known as the Human Leukocyte Antigens (HLA) is localised to the short arm of chromosome six. The HLA class 1 antigens, HLA-A, -B and -C are highly polymorphic glycoproteins expressed on the cell surface of most nucleated cells in the body. READ MORE

7. 5. Allogeneic stem cell transplantation in children : identification and prevention of complications : adoptive transfer of EBV-immunity

   Author : Åsa Gustafsson Jernberg; Karolinska Institutet; Karolinska Institutet; []
   Keywords : Children; CTL; EBV; Graft-versus-leukaemia; Stemcell transplantation; unrelated;

   Abstract : Allogeneic stem cell transplantation (SCT) can cure leukaemia, aplastic anaemia, and some inborn errors of metabolism and immunodeficiencies in children. As only 113 of patients who need SCT have an HLA-identical sibling, the use of alternative donors has increased, to over 50% of all paediatric SCTs at our centre. READ MORE