Search for dissertations about: "ureas"
Showing result 1 - 5 of 14 swedish dissertations containing the word ureas.
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1. The Synthesis and Use of Certain Pyridine Derivatives as Modulators of the G-protein Coupled Receptors mGlu5 and P2Y12
Abstract : The glutamatergic mGlu5 receptor and the purinergic P2Y12 receptor are two important targets in the development of novel treatments of gastroesophageal reflux disease (GERD) and thrombosis, respectively. Synthesis was developed to investigate the structure-activity relationships (SAR) of a novel series of 2-alkynylpyridine derivatives as mGluR5 antagonists. READ MORE
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2. Crystal Engineering of Some 2-Pyrimidinones and Unsymmetrical Ureas
Abstract : .... READ MORE
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3. Kinetic studies of the decomposition of some carbamates, ureas and related cyclic compounds
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4. Helicobacter pylori cell surface interactions with glycosaminoglycans. Identification and characterisation of proteins binding to heparin/heparan sulphate
Abstract : Helicobacter pylori is a gastric pathogen which cause chronic type B gastritis and peptic ulcer disease. H. pylori produces virulence factors such as urease, vacuolating cytotoxin VacA, cag pathogenicity island-associated proteins, flagella and adhesins. READ MORE
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5. Mechanistic Studies of Dinuclear Metalloenzymes - A Model Approach
Abstract : With the goal to study the mechanisms of dinuclear metalloenzymes, a new line of synthetic and computational models were prepared and studied. Mixed imidazole and carboxylate multidentate complexes were synthesized to better simulate carboxylate-rich ligand environments. READ MORE