Search for dissertations about: "ursodeoxycholic acid"

Showing result 1 - 5 of 12 swedish dissertations containing the words ursodeoxycholic acid.

2. 1. Intrahepatic cholestasis of pregnancy

   Author : Anna Glantz; Göteborgs universitet; []
   Keywords : Intrahepatic cholestasis of pregnancy ICP ; pruritus; fetal risk; ursodeoxycholic acid; dexamethasone; ABCB4-gene; haplotypes; sulphated progesterone metabolites;

   Abstract : Intrahepatic cholestasis of pregnancy (ICP) is a condition that has been reported to be associated with an increased fetal risk. A prospective study of ICP was conducted in the Västra Götaland region of Sweden between February 1, 1999 and January 31, 2002. READ MORE

4. 2. Inflammatory bowel disease, colorectal neoplasia and treatment with ursodeoxycholic acid in primary sclerosing cholangitis

   Author : Lina Lindström; Karolinska Institutet; Karolinska Institutet; []
   Keywords : inflammatory bowel disease;

   Abstract : Background: Primary sclerosing cholangitis (PSC) is a chronic cholestatic liver disease closely associated with inflammatory bowel disease. PSC is progressive and ultimately leads to death or need for liver transplantation. Patients are also at high risk of developing colorectal neoplasia (CRN). READ MORE

5. 3. Steroids and bile acids in intrahepatic cholestasis of pregnancy : effects of treatment with ursodeoxycholic acid

   Author : Ling-Jie Meng; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : A method permitting simultaneous analysis of individual steroid hormone metabolites and bile acids in different forms of conjugation in serum and urine was established. Total bile acids and neutral steroids were extracted from human serum or urine with octadecylsilane-bonded silica, separated into different groups of conjugates by anion-exchange chromatography and analyzed by fast atom bombardment mass spectrometry. READ MORE

6. 4. On the regulation of hepatic cholesterol and bile acid metabolism in gallstone patients

   Author : Carl-Gustaf Hillebrant; Karolinska Institutet; Karolinska Institutet; []
   Keywords : Bile acid synthesis; biliary lipids; cholesterol synthesis; cholesterol 7a-hydroxylase; cholesterol synthesis inhibitor; chenodeoxycholic acid; cholestyramine; 7a-hydroxy-4-cholesten-3-one; HMG CoA reductase; lathosterol; lipoproteins; lithocholic acid; plasma apheresis; ursodeoxycholic acid;

   Abstract : The liver plays an important role in the regulation of cholesterol homeostasis, therefore also in the pathogenesis of arteriosclerosis and gallstone disease. The quantitatively most important way by which cholesterol is removed from the human body is via the bile, either as free cholesterol or after transformation to bile acids. READ MORE

7. 5. Crohn's disease in Stockholm County : epidemiological panorama and associated gallstone disease

   Author : Annika Lapidus; Karolinska Institutet; Karolinska Institutet; []
   Keywords : Bile acid; biliary lipids; bilirubin; cholesterol; colon; Crohn s disease; epidemiology; gallstone; ileal resection; incidence; prevalence; prognosis.;

   Abstract : Crohn's disease is a chronic inflammatory bowel disease of obscure etiology, affecting any part of the gastrointestinal tract but the ileocaecal region in particular. The annual incidence has gradually been increasing, and the clinical pattern has changed; a shift towards colorectal involvement as well as an increasing number of elderly patients has been observed. READ MORE