Search for dissertations about: "uveoscleral"

Found 3 swedish dissertations containing the word uveoscleral.

  2. 1. The prostanoid FP receptor and uveoscleral outflow : A study of FP receptor expression and functions in the eye

    Author : Anette Ocklind; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Genetics; Prostanoid FP receptor; tissue distribution; ciliary muscle; iris sphincter muscle; extracellularmatrix; actin; prostaglandin F2a; latanoprost; Genetik; Clinical genetics; Klinisk genetik; Pathology; patologi;

    Abstract : Prostaglandin F2α is a prostanoid FP receptor agonist which acts as an intraocular pressure-lowering agent by increasing the uveoscleral outflow of aqueous humour through the ciliary muscle. The aim of this, thesis was to investigate possible mechanisms of the increased uveoscleral outflow induced by prostaglandin F2α and its analogue latanoprost acid. READ MORE

  4. 2. Aspects on prostanoid and cholinergic effects on aqueous humour dynamics in human eyes

    Author : Christina Lindén; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Aqueous flow; blood-aqueous barrier; flare; human; intraocular pressure IOP ; latanoprost; physostigmine; prostaglandins; uveoscleral flow;

    Abstract : The discovery of the ocular hypotensive effect of topically applied prostaglandins (PGs) has raised a number of questions about the mechanisms of action involved. The aim of the present thesis was to answer some of these questions. READ MORE

  5. 3. Aspects of aqueous humor dynamics : Studies in vivo and in vitro

    Author : Maria Samuelsson-Almén; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Physiology and anatomy; Aqneous humor flow; intraocular pressure; adenylate cyclase; nonpigmented ciliary epithelium; pituitary adenylate cyclase-activating polypeptide; vasoactive intestinal polypeptide; dopamine; prostaglandin; Fysiologi och anatomi; Physiology and pharmacology; Fysiologi och farmakologi; Physiology; fysiologi;

    Abstract : The purpose of the present investigation was to study the effects of PGF2α-l-isopropylester, some neuropeptides, and pharmacological agents on aqueous humor dynamics and intraocular pressure (IOP) in vivo and on adenylate cyclase activity in the nonpigmented ciliary epithelium (NPE) in vitro.Pituitary adenylate cyclase-activating polypeptide (PACAP) and vasoactive intestinal polypeptide (VIP) caused a dose-dependent increase in cAMP formation, indicating that the NPE contains receptors for PACAP and VIP coupled to adenylate cyclase activation. READ MORE